Results 31 to 40 of about 101,866 (227)

On the Problem of Computing the Probability of Regular Sets of Trees [PDF]

open access: yes, 2015
We consider the problem of computing the probability of regular languages of infinite trees with respect to the natural coin-flipping measure. We propose an algorithm which computes the probability of languages recognizable by \emph{game automata}.
Michalewski, Henryk, Mio, Matteo
core   +4 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

On the Bernoulli Automorphism of Reversible Linear Cellular Automata

open access: yes, 2015
This investigation studies the ergodic properties of reversible linear cellular automata over $\mathbb{Z}_m$ for $m \in \mathbb{N}$. We show that a reversible linear cellular automaton is either a Bernoulli automorphism or non-ergodic.
Chang, Chih-Hung, Chang, Huilan
core   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Cost Preserving Bisimulations for Probabilistic Automata [PDF]

open access: yes, 2013
Probabilistic automata constitute a versatile and elegant model for concurrent probabilistic systems. They are equipped with a compositional theory supporting abstraction, enabled by weak probabilistic bisimulation serving as the reference notion for ...
Hermanns, Holger, Turrini, Andrea
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A Fibrational Approach to Automata Theory

open access: yesarXiv: Formal Languages and Automata Theory, 2015
For predual categories C and D we establish isomorphisms between opfibrations representing local varieties of languages in C, local pseudovarieties of D-monoids, and finitely generated profinite D-monoids. The global sections of these opfibrations are shown to correspond to varieties of languages in C, pseudovarieties of D-monoids, and profinite ...
Chen, Liang-Ting, Urbat, Henning
openaire   +5 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

On cascade products of answer set programs

open access: yes, 2014
Describing complex objects by elementary ones is a common strategy in mathematics and science in general. In their seminal 1965 paper, Kenneth Krohn and John Rhodes showed that every finite deterministic automaton can be represented (or "emulated") by a ...
Antić, Christian
core   +1 more source

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