Results 91 to 100 of about 106,876 (300)

Gait Recognition by Dynamic Cues

, 2008
Many studies have now shown that it is possible to recognize people by the way they walk. As yet there has been little formal study of people recognition using the kinematic-related gait features.
Mark S. Nixon, Nixon, Mark, Bouchrika, Imed, Imed Bouchrika   +3 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Detection and Classification of Overlapping Cell Nuclei in Cytology Effusion Images Using a Double-Strategy Random Forest

Applied Sciences, 2018
Due to the close resemblance between overlapping and cancerous nuclei, the misinterpretation of overlapping nuclei can affect the final decision of cancer cell detection. Thus, it is essential to detect overlapping nuclei and distinguish them from single
Khin Yadanar Win, Somsak Choomchuay, Kazuhiko Hamamoto, Manasanan Raveesunthornkiat   +3 more
doaj   +1 more source

Self-calibrating view-invariant gait biometrics

, 2010
We present a new method for view-point independent gait biometrics. The system relies on a single camera, does not require camera calibration and works with a wide range of camera-views.
Goffredo, Michela, Nixon, Mark, Bouchrika, Imed, Carter, John   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Hybrid deep learning and handcrafted feature fusion for pneumonia detection in chest X-rays

Journal of Electrical Systems and Information Technology
Pneumonia is a major cause of death worldwide, with nearly 2.2 million deaths every year, including over 700,000 children aged five years and below. Chest X-ray (CXR) imaging is the standard method taken up to diagnose pneumonia; however, such image ...
Mohammad Farukh Hashmi, Amreen Aijaz Husain, Deepali M Kotambkar, Konapala Dileep Kumar   +3 more
doaj   +1 more source

A product data management integrated product configuration and assembly process planning environment. [PDF]

, 2002
This paper reports part of the results of a 3 year project carried out at Cranfield University in collaboration with companies in the automotive and aerospace industry, aiming to develop new methodologies for computer aided assembly process planning ...
Bowland, N. W., Gao, James X.
core   +1 more source