Results 231 to 240 of about 1,200,969 (291)

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Legal document summarization: a short review. [PDF]

Front Artif Intell
Nazly M, Yapa P.
europepmc   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Neuro-symbolic reasoning engine for tax optimisation. [PDF]

Front Artif Intell
Veeramani K, Joseph N A, M P.
europepmc   +1 more source

Hybrid artificial intelligence framework for patient emotion recognition in dentistry. [PDF]

Front Oral Health
Aryadi A, Pratomo HG, Wattanachote K, Ratanawimon T, Phanchantraurai P, Suphasri-Itsara W, Phumpatrakom P, Inglam S, Suebnukarn S.   +8 more
europepmc   +1 more source

Special Issue of the Journal of Automated Reasoning on "Automated Reasoning for Security Protocol Analysis"

, 2006
Cuellar, J., Rustinowitch, M., Basin, D., Armando, Alessandro, Viganò, L.   +4 more
core  

Distillation of a Locally Deployable 8B Language Model for Lung Histology Abstraction: A 33-Report Proof-of-Concept Study. [PDF]

J Multidiscip Healthc
Wiyanti DT, Hsu MH, Nugroho DCA.
europepmc   +1 more source

Evaluating the Accuracy of Large Language Models in Risk-of-Bias Assessment Using Version 2 of the Cochrane Risk-of-Bias Tool for Randomized Trials: Exploratory Feasibility Study. [PDF]

J Med Internet Res
Lai YJ, Lin SH, Liu JW.
europepmc   +1 more source

Scaffolded AI-Supported Problem-Based Learning for Medical Interns: Exploratory Retrospectively Registered Randomized Controlled Evaluation With a Voluntary Feasibility Follow-Up. [PDF]

JMIR Med Educ
Zhao Z, Wu B, Tian S, Hu H, Hao P.
europepmc   +1 more source