Results 151 to 160 of about 4,044,436 (277)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

An Automated Scoring of Clinical Asthma Score: Proof of Concept and the Future Possibility. [PDF]

Crit Care Explor, 2021
Al-Omar S, Lepage-Farrell A, Kawaguchi A, Emeriaud G.   +3 more
europepmc   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

An automated computational data pipeline to rapidly acquire, score, and rank toxicological data for ecological hazard assessment [PDF]

Christopher M. Schaupp, G Byrne, Manli Chan, Derik E. Haggard, Monique Hazemi, Mark D. Jankowski, Carlie A. LaLone, Andrea LaTier, Kali Z. Mattingly, Jennifer H. Olker, James Renner, Bhaskar Sharma, Daniel L. Villeneuve   +12 more
openalex   +1 more source

High‐throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium [PDF]

, 2016
Mustapha Abubakar, William Howat, Frances Daley, Lila Zabaglo, Leigh‐Anne McDuffus, Fiona M. Blows, Penny Coulson, H. Raza Ali, Javier Benı́tez, Roger L. Milne, Hermann Brenner, Christa Stegmaier, Graham J. Mann, Jenny Chang‐Claude, Anja Rudolph, Hans‐Peter Sinn, Fergus J. Couch, Rob A.�E.�M. Tollenaar, Peter Devilee, Jonine D. Figueroa, Mark E. Sherman, Jolanta Lissowska, Stephen M. Hewitt, Diana Eccles, Maartje J. Hooning, Antoinette Hollestelle, John W.M. Martens, Rob B. van der Luijt, kConFab Investigators, Manjeet K. Bolla, Qin Wang, Michael E. Jones, Minouk J. Schoemaker, Annegien Broeks, Flora E. van Leeuwen, Laura van’t Veer, Anthony J. Swerdlow, Nick Orr, Mitch Dowsett, Douglas F. Easton, Marjanka K. Schmidt, Paul D.P. Pharoah, Montserrat García‐Closas   +42 more
openalex   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Automated scoring for a Tablet-based Rey Figure copy task differentiates constructional, organisational, and motor abilities. [PDF]

Sci Rep, 2021
Petilli MA, Daini R, Saibene FL, Rabuffetti M.   +3 more
europepmc   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

A comparison of an automated body condition scoring system from DeLaval with manual, non-automated, method.

, 2020
P. Zieltjens
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source