Results 51 to 60 of about 1,140,236 (298)

Challenges to support automated random testing for dynamically typed languages [PDF]

, 2011
International audienceAutomated random testing is a proven way to identify bugs and precondition violations, and this even in well tested libraries.
Bergel, Alexandre, Ducasse, Stéphane, Oriol, Manuel   +2 more
core   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Automated Testing of Information Security Devices, Which Represented as Removable Media, and its Issues

Безопасность информационных технологий, 2016
This article describesissues, arising in automatedtesting of information security devices, which represented as removable media. These devices have their own operational system, whichimposes restrictions on its testing process.
Anatoliy Petrovich Durakovskiy, Ivan Alexandrovich Korsakov, Anton Anatolievich Abramov   +2 more
doaj  

From Digital Twins to Digital Twin Prototypes: Concepts, Formalization, and Applications

IEEE Access
The transformation to Industry 4.0 also transforms the processes of developing intelligent manufacturing production systems. Digital twins may be employed to advance the development of these new (embedded) software systems.
Alexander Barbie, Wilhelm Hasselbring
doaj   +1 more source

The Search for the Laws of Automatic Random Testing

, 2012
Can one estimate the number of remaining faults in a software system? A credible estimation technique would be immensely useful to project managers as well as customers.
Furia, Carlo A., Meyer, Bertrand, Oriol, Manuel, Tikhomirov, Andrey, Wei, Yi   +4 more
core   +1 more source

The multifocal pattern electroretinogram in chloroquine retinopathy [PDF]

, 2004
Purpose: Optimal screening for ocular toxicity caused by chloroquine and hydroxychloroquine is still controversial. With the multifocal pattern electroretinogram (mfPERG), a new electrophysiological technique has recently become available to detect early
Arden, G. B., Berninger, T., Neubauer, A. S., Rudolph, G., Stiefelmeyer, S.   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Research on AFDX network configuration testing technology

Xibei Gongye Daxue Xuebao
The terminal system, as a key part of AFDX network data transmission, determines the communication performance of the entire AFDX network. In order to test the functionality of the verification end system and evaluate the transmission performance of the ...
CHEN Fang, LYU Guangzhe, LIN Wei, HOU Xixi, MA Chunyan   +4 more
doaj   +1 more source

Force-Control for the Automated Footwear Testing System [PDF]

, 2005
The Automated Footwear Testing System (AFTS) is a robotic system designed to replicated the movement and loading of a shoe as it contacts the ground during common human movements.
Lewis, Greg
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source