Results 31 to 40 of about 7,812,445 (274)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Genetic Algorithm as Automated Valuation Model Component in Real Estate Investment Decisions System

open access: yesReal Estate Management and Valuation, 2020
Every real-estate related investment decision making process calls for the careful analysis of available information even though it is often carried out in conditions of uncertainty.
Chmielewska Aneta   +2 more
doaj   +1 more source

Automated real estate valuation disruption in the Smart Cities context [PDF]

open access: yes, 2022
[EN] The technological revolution has given rise to a new scenario for action, the Smart Cities. Its influence in the field of real estate valuation is transferred to the Automated Valuation Models (AVM) as tools that allow us to deal with the volume ...
Ramírez Pacheco, Gema   +1 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

IMPROVING THE QUALITY OF PRODUCTS ON THE BASIS OF THE SYSTEM OF FUNCTIONAL-COST ANALYSIS

open access: yesНадежность и качество сложных систем, 2023
Background. Modern methods of increasing production efficiency and improving product quality, using functional cost analysis (FSA), assign the main role to the valuation of business processes.
O.N. Pchelnikova-Grotova
doaj   +1 more source

Practice briefing – automated valuation models (AVMs): their role, their advantages and their limitations

open access: yes, 2020
Purpose – The current state-of-the-art recognises three traditional valuation approaches. The current division is not sufficient to explain systematically all features that drive the development and usage of automated valuation models.
Des Rosiers, François   +3 more
core   +1 more source

Automated Valuation Modelling

open access: yes, 2013
Market value predictions for residential properties are important for investment decisions and the risk management of households, banks, and real estate developers. The increased access to market data has spurred the development and application of Automated Valuation Models (AVMs), which can provide appraisals at low cost.
Schulz, Rainer   +2 more
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The Use and Benefits of Automated Valuation Models: Results and Insights from the 2019 AVM Survey

open access: yes, 2020
In 2019 the IAAO in partnership with the Lincoln Institute surveyed the IAAO membership on the use of Automated Valuation Models (AVMs) for the assessment of property.
Bidanset, Paul, PhD (Candidate)   +1 more
core   +1 more source

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