Results 41 to 50 of about 87,618 (263)

Wave-function positivization via automatic differentiation

Physical Review Research, 2020
We introduce a procedure to systematically search for a local unitary transformation that maps a wave function with a nontrivial sign structure into a positive-real form. The transformation is parametrized as a quantum circuit compiled into a set of one-
Giacomo Torlai, Juan Carrasquilla, Matthew T. Fishman, Roger G. Melko, Matthew P. A. Fisher   +4 more
doaj   +1 more source

Distributed Automatic Differentiation for Ptychography

Procedia Computer Science, 2017
Abstract Synchrotron radiation light source facilities are leading the way to ultrahigh resolution X-ray imaging. High resolution imaging is essential to understanding the fundamental structure and interaction of materials at the smallest length scale possible.
Youssef S. G. Nashed, Tom Peterka, Junjing Deng, Chris Jacobsen   +3 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimization with Time and Frequency Constraints Using Automatic Differentiation: Application to an Aircraft Electrical Power Channel

Applied Sciences
The ordinary differential equations used to model a dynamic system can evolve during the simulation in circumstances where unpredictable events occur, more specifically, in regard to the domain of power electronics, for example, static converters will ...
Lucas Agobert, Laurent Gerbaud, Benoit Delinchant   +2 more
doaj   +1 more source

Fully differentiable optimization protocols for non-equilibrium steady states

New Journal of Physics, 2021
In the case of quantum systems interacting with multiple environments, the time-evolution of the reduced density matrix is described by the Liouvillian.
Rodrigo A Vargas-Hernández, Ricky T Q Chen, Kenneth A Jung, Paul Brumer   +3 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Automatic Functional Differentiation in JAX

CoRR, 2023
We extend JAX with the capability to automatically differentiate higher-order functions (functionals and operators). By representing functions as a generalization of arrays, we seamlessly use JAX's existing primitive system to implement higher-order functions.
openaire   +3 more sources

Automatic Differentiation for error analysis [PDF]

Proceedings of Tools for High Energy Physics and Cosmology — PoS(TOOLS2020), 2021
Contribution to Tools for High Energy Physics and Cosmology - TOOLS2020.
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Optimizing differential equations to fit data and predict outcomes

Ecology and Evolution, 2023
Many scientific problems focus on observed patterns of change or on how to design a system to achieve particular dynamics. Those problems often require fitting differential equation models to target trajectories.
Steven A. Frank
doaj   +1 more source