Results 171 to 180 of about 54,150 (263)

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Influence of dairy farms' characteristics and technological level on attitude towards augmented reality. [PDF]

Sci Rep
Pinna D, Sara G, Cresci R, Petronella A, Todde G, Atzori AS, Caria M.   +6 more
europepmc   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

Advanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole, Andrew Lai, Alexander Quinn, Marianne Gillard, Dominic Guanzon, Katherin Scholz‐Romero, Alexis Salas‐Burgos, Bastián Lillo Dapremont, Rohan Lourie, Naven Chetty, Richard Lobb, Kate Beecher, Amy E. McCart Reed, Kaltin Ferguson, Biao Sun, Yaowu He, John D. Hooper, Carlos Salomon   +17 more
wiley   +1 more source

Artificial intelligence in transitional care: practice, promise, and pitfalls-a scoping review. [PDF]

Front Digit Health
Fakha A, Boonstra A.
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

A call for action to strengthen stakeholder readiness for ICF data exchange in European health data space: a structured narrative review. [PDF]

Front Public Health
Nieminen L, Anttila H, Ketamo H, Zampolini M, Martinuzzi A, Della Mea V.   +5 more
europepmc   +1 more source

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

Advanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang, Jinlei Jiang, Zhengting Wang, Shuqi Liu, Wei Wang, Xi Chen, Qirui Zhao, Xinyuan Cui, Cheng Zhou, Shengsheng Cui, Daxiang Cui   +10 more
wiley   +1 more source

Benchtop NMR signal enhancement of metabolites in urine extract using SABRE. [PDF]

Chem Commun (Camb)
Fleischer S, Yang J, Ausmees K, Reile I, MacKinnon N, Korvink JG, Lehmkuhl S.   +6 more
europepmc   +1 more source

Unity Quantum Yield of High‐Entropy Quantum Dots Composited With Photonic Crystals for Information Encryption

Advanced Science, EarlyView.
This study first extends the high‐entropy concept to I‐III‐VI quantum dots (QDs) and synthesizes CZCrGSe/ZnSe/ZnS core/shell/shell QDs with a record photoluminescence quantum yield (PLQY) of 100%. Their ZnSe/ZnS double shell efficiently passivates defects and boosts structural stability.
Maoyuan Huang, Ziqiang Tian, Binkun Xie, Haiyang Li, Bo Tan, Chang He, Shiliang Mei, Wanlu Zhang, Changchun Wang, Ruiqian Guo   +9 more
wiley   +1 more source

Mapping the global public health intelligence landscape: a multiregional cross-sectional survey. [PDF]

BMC Public Health
Méndez-Brito A, Kerber R, Spiteri G, Tetuh KM, Fehr A, Manthey C, Alinon KN, Esquevin S, Squires N, Jansen A, Correa-Martínez CL.   +10 more
europepmc   +1 more source