Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
SwarMAV: A Swarm of Miniature Aerial Vehicles [PDF]
As the MAV (Micro or Miniature Aerial Vehicles) field matures, we expect to see that the platform's degree of autonomy, the information exchange, and the coordination with other manned and unmanned actors, will become at least as crucial as its ...
De Nardi, Renzo, Holland, Owen
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Perceiving Pain in Others: Automatic and Controlled Mechanisms [PDF]
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Baird +93 more
core +2 more sources
A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg +5 more
wiley +1 more source
Tax-Co-ordination in Europe: Assessing the First Years of the EU-Savings Taxation Directive [PDF]
This paper reviews the economic effects of the EU Savings Taxation Directive. The Directive aims at enabling taxation of foreign interest payments received by individuals in accordance with the rules of their State of residence. The data suggest that the
Gaëtan J.A. Nicodème +1 more
core +3 more sources
Interconnecting Systems Using Machine-Actionable Data Management Plans – Hackathon Report
The common standard for machine-actionable Data Management Plans (DMPs) allows for automatic exchange, integration, and validation of information provided in DMPs. In this paper, we report on the hackathon organised by the Research Data Alliance in which
João Cardoso +2 more
doaj +1 more source
FATCA AND CRS COMPLIANCE: BRAZIL’S TREND TOWARDS AUTOMATIC EXCHANGE OF INFORMATION [PDF]
Although legislation allowing tax authorities to have access to banking information of taxpayers be in force for several years and Brazil be entering into agreements providing for even automatic exchange of taxpayers’ banking information, the extent of Brazil’s constitutional protection of banking secrecy is not yet clear and, accordingly, so is ...
openaire +1 more source
Innovating Aircraft Repair Processes: The Role of Digitalization in Sustainability
This research explores how digitalization—by storing detailed non‐destructive testing data in structured DICONDE databases and creating a standard data model of the component—innovates aviation maintenance and repair processes. Coupled with a developed state‐based simulation model, it enables data‐driven, sustainable repair strategies that reduce waste,
Johanna Aigner +3 more
wiley +1 more source
Towards Avatars with Artificial Minds: Role of Semantic Memory [PDF]
he first step towards creating avatars with human-like artificial minds is to give them human-like memory structures with an access to general knowledge about the world. This type of knowledge is stored in semantic memory.
Duch, Wlodzislaw +2 more
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