Results 131 to 140 of about 23,159 (233)

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Volume 78, Issue 5, Page 1045-1061, May 2026.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Design concepts and performance of NASA X-band (7162 MHz/8415 MHz) transponder for deep-space spacecraft applications [PDF]

The design concepts and measured performance characteristics are summarized of an X band (7162 MHz/8415 MHz) breadboard deep space transponder (DSP) for future spacecraft applications, with the first use scheduled for the Comet Rendezvous Asteroid Flyby (
Kermode, A. W., Mysoor, N. R., Perret, J. D.   +2 more
core   +1 more source

Cascaded Tilt Control‐Based Frequency Regulation of Renewable Energy Integrated Three Area Power System With Smart Transformer

Engineering Reports, Volume 8, Issue 5, May 2026.
Introducing a cascaded TI–TID secondary controller (SFO‐tuned) for a renewable‐integrated three‐area grid with HVDC and smart transformers modulating voltage‐dependent loads, achieving faster settling, lower overshoot, and robust frequency/tie‐line regulation under ±20% load changes versus conventional TI/TID baselines.
Sanjeev Kumar Bhagat, Naladi Ram Babu, Pooja Jha, Nekkanti Rajesh, K. R. K. V. Prasasd, Abhishek Thakur, Moustafa Ahmed Ibrahim, Wulfran Fendzi Mbasso   +7 more
wiley   +1 more source

Evaluation of Acephate Metabolites Generated by Zebrafish (Danio rerio) Using LC–HRMS and Metabolomics Approach

Journal of Applied Toxicology, Volume 46, Issue 5, Page 1679-1686, May 2026.
ABSTRACT Acephate is an organophosphate insecticide widely used. This pesticide can be metabolized into methamidophos, a molecule highly toxic. Both have demonstrated the ability to promote serious toxic effects on nontarget organisms and have been identified in surface waters around the world. Therefore, it is important to understand their behavior in
Mariana Laiz Silva de Lima, Lucas Rodrigues Cunha, Karina Taciana Santos Rubio, Maria Elvira Poleti Martucci   +3 more
wiley   +1 more source

Frequency‐Constrained Real‐Time Co‐Optimisation of Energy and Regulation Reserve Integrated With Battery Energy Storage Systems

IET Smart Grid
This paper proposes a real‐time co‐optimisation framework integrated with automatic generation control (RTC‐AGC) for the optimal reallocation of energy and regulation reserves in real‐time electricity markets.
Mohammad Amin Mirzaei, Masood Parvania
doaj   +1 more source

Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia

PROTEOMICS, Volume 26, Issue 5, Page 59-68, May 2026.
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives, James M. Fulcher, Alex R. Bautista, Reta Birhanu Kitata, Sarah M. Williams, David A. Bennett, Philip L. De Jager, Vladislav A. Petyuk   +7 more
wiley   +1 more source

Biophysical characterization of Cyclophilin B reveals membrane localization as its primary functional determinant as a prolyl isomerase

Protein Science, Volume 35, Issue 5, May 2026.
Abstract The endoplasmic reticulum (ER) provides a specialized environment for the folding of secreted and membrane proteins, a process supported by many different chaperones. Among these chaperones, peptidyl‐prolyl cis/trans isomerases (PPIases) catalyze a rate‐limiting conformational step in protein folding, yet the principles governing isoform ...
Sarah C. DeVoe, Thomas C. Yost, Ashley J. Newton, Gavin A. Grever, Melissa Fernandez Ayala, Wendell P. Griffith, Robert D. Latvala, Philipp A. M. Schmidpeter   +7 more
wiley   +1 more source

An initial assessment of the performance achieved by the Seasat-1 radar altimeter [PDF]

The results of an initial on-orbit engineering assessment of the performance achieved by the radar altimeter system flown on SEASAT-1 are presented.
Townsend, W. F.
core   +1 more source

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

Aging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima, Taiga Nagamune, Saori Tada, Daiki Watanabe, Nao Tokuda, Takashi Yamada, Akiko Hashimoto‐Hachiya, Sayaka Higo‐Yamamoto, Kohei Kido, Noriyuki Nagaoka, Aoi Ikedo, Yuuki Imai, Ryo Fujita, Seiya Mizuno, Satoru Takahashi, Katsutaka Oishi, Satoru Ato, Riki Ogasawara   +17 more
wiley   +1 more source

SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL‐Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development

Aging Cell, Volume 25, Issue 5, May 2026.
Mechanistic study of AGEs‐induced OA progression via SIRT1/RANKL/RANK signaling‐mediated osteoclast–chondrocyte communication and cellular senescence. ABSTRACT Advanced glycation end products (AGEs) accumulate with aging and metabolic stress and are increasingly implicated in osteoarthritis (OA) pathology.
Yizhou Li, Jian Wu, Rui Liu, Qiang Li, Fei Xue   +4 more
wiley   +1 more source