Results 61 to 70 of about 218,873 (322)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Automatic data collection and annotation system for a pose estimation dataset designed for grasping detection

工程科学学报
Robotic grasping has extensive applications in fields such as logistics sorting, automated assembly, and medical surgery. Grasping detection is an important step in robotic grasping.
Peng CHEN, Yong BAI, Hanxiang SUN
doaj   +1 more source

Automatic classification of the cerebral vascular bifurcations using dimensionality reduction and machine learning

Neuroscience Informatics, 2022
This paper presents a method for the automatic labeling of vascular bifurcations along the Circle of Willis (CoW) in 3D images. Our automatic labeling process uses machine learning as well as dimensionality reduction algorithms to map selected ...
Ibtissam Essadik, Anass Nouri, Raja Touahni, Romain Bourcier, Florent Autrusseau   +4 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Automatic group-wise whole-brain short association fiber bundle labeling based on clustering and cortical surface information

BioMedical Engineering OnLine, 2020
Background Diffusion MRI is the preferred non-invasive in vivo modality for the study of brain white matter connections. Tractography datasets contain 3D streamlines that can be analyzed to study the main brain white matter tracts.
Andrea Vázquez, Narciso López-López, Josselin Houenou, Cyril Poupon, Jean-François Mangin, Susana Ladra, Pamela Guevara   +6 more
doaj   +1 more source

Annotating Object Instances with a Polygon-RNN

, 2017
We propose an approach for semi-automatic annotation of object instances. While most current methods treat object segmentation as a pixel-labeling problem, we here cast it as a polygon prediction task, mimicking how most current datasets have been ...
Castrejon, Lluis, Fidler, Sanja, Kundu, Kaustav, Urtasun, Raquel   +3 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

ALICE Software: Machine learning & computer vision for automatic label extraction [PDF]

, 2022
Arianna Salili‐James, Ben Scott, Vincent Smith   +2 more
openalex   +1 more source

Rural Settlement Segmentation in Large-Scale Remote Sensing Imagery Using MSF-AL Auto-Labeling and the SELPFormer Model

Remote Sensing
Accurate delineation of rural settlements at large spatial extents is fundamental to territorial spatial governance, rural revitalization, and the improvement of human living environments.
Qian Zhou, Yongqi Sun, Yanjun Tian, Qiqi Deng, Shireli Erkin, Yongnian Gao   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source