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Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu   +11 more
wiley   +1 more source

A comparison of clustering algorithms for automatic modulation classification

Expert Systems With Applications, 2020
Abstract In this paper, the k-means, k-medoids, fuzzy c-means, Density-Based Spatial Clustering of Applications with Noise (DBSCAN), Ordering Points To Identify the Clustering Structure (OPTICS), and hierarchical clustering algorithms (with the addition of the elbow method) are examined for the purpose of Automatic Modulation Classification (AMC ...
Jacques P Mouton, Melvin Ferreira
exaly   +2 more sources

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