Results 151 to 160 of about 7,489 (214)

Human TET2-Mutant Clonal Hematopoiesis Expansion Is Driven by Distinct Inflammatory Signaling Responses in Stem Cells Versus Myeloid Progeny. [PDF]

Blood Cancer Discov
Huerga Encabo H, D'Agostino G, Sturgess K, Lord AE, Jong ED, Ferrelli A, Sharma A, Mian SA, Habel K, Llorian-Sopena M, Ramesh AP, Mohamad Nor F, Foissner H, Garcia-Albornoz M, Graver L, Papazoglou D, Ngo S, Anjos-Afonso F, Ariza-McNaughton L, Ficz G, Bonnet D.   +20 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Quantification of Automatic Speech Recognition System Performance on d/Deaf and Hard of Hearing Speech. [PDF]

Laryngoscope
Zhao R, Choi ASG, Koenecke A, Rameau A.
europepmc   +1 more source

microeco 2: A comprehensive R package for downstream analysis of microbiome omics data

iMeta, EarlyView.
The current version 2.0 of the microeco package represents a substantial update compared to the previously published version. Key enhancements include the addition of new classes, integration of a broader suite of analytical methods, a comprehensive overhaul of the parameter system, improved connectivity between statistical analysis and visualization ...
Chi Liu, Xiangzhen Li, Felipe R. P. Mansoldo, Tong Chen, Fanzheng Meng, Ruixiang Tang, Siyu Zhou, Qinghua Yang, Ruixin Shao, Minjie Yao   +9 more
wiley   +1 more source

A publishing infrastructure for Artificial Intelligence (AI)-assisted academic authoring. [PDF]

J Am Med Inform Assoc
Pividori M, Greene CS.
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Automatic Detection of Articulatory-Based Disfluencies in Primary Progressive Aphasia. [PDF]

IEEE J Sel Top Signal Process
Lian J, Zhou X, Guo C, Ye Z, Ezzes Z, Vonk JMJ, Morin B, Baquirin D, Miller Z, Gorno-Tempini ML, Anumanchipalli GK.   +10 more
europepmc   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Understanding Language through TalkBank. [PDF]

Curr Dir Psychol Sci
MacWhinney B.
europepmc   +1 more source