Results 261 to 270 of about 339,980 (298)

Dissolving Microneedle for Maintaining the Integrity of HPV Virus‐Like Particles Enabling Durable Sterile Protection Across Various Mucosal Tissues

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim   +12 more
wiley   +1 more source

Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin

open access: yesAdvanced Healthcare Materials, EarlyView.
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis   +6 more
wiley   +1 more source

Toward Noninvasively Imaging pH at the Surface of Implanted Orthopedic Devices in Live Rabbits Using X‐ray Excited Luminescence Chemical Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
Imaging pH in a live rabbit at the surface of a sensor‐coated titanium plate using X‐ray excited luminescent chemical imaging (XELCI). A raster scanning X‐ray beam generates radioluminescence from a spot on the sensor, and the luminescence passes through the tissue and is collected at two wavelengths to determine local pH.
Unaiza Uzair   +6 more
wiley   +1 more source

Effectiveness of a self-help guide during a temporary alcohol abstinence challenge: a randomized controlled trial. [PDF]

open access: yesAlcohol Alcohol
Esselink A   +5 more
europepmc   +1 more source

Stem cell-derived cardiomyocytes expressing a dominant negative pacemaker HCN4 channel do not reduce the risk of graft-related arrhythmias. [PDF]

open access: yesFront Cardiovasc Med
Wulkan F   +12 more
europepmc   +1 more source

iPSC-Derived Biological Pacemaker-From Bench to Bedside. [PDF]

open access: yesCells
Vo QD   +8 more
europepmc   +1 more source

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