Results 31 to 40 of about 339,980 (298)

Control of automated behaviour: Insights from the Discrete Sequence Production task

Frontiers in Human Neuroscience, 2013
Work with the discrete sequence production (DSP) task has provided a substantial literature on discrete sequencing skill over the last decades. The purpose of the current article is to provide a comprehensive overview of this literature and of the ...
Elger eAbrahamse, Marit eRuitenberg, Elian eDe Kleine, Willem B Verwey   +3 more
doaj   +1 more source

Automated Symbolic Orienting: The missing link

Frontiers in Psychology, 2012
Attention can be controlled either exogenously, driven by the stimulus features, or endogenously, driven by the internal expectancies about events in the environment.
Jelena eRistic, Mathieu eLandry, Alan eKingstone   +2 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

The enemy within: propagation of aberrant corticostriatal learning to cortical function in Parkinson's disease

Frontiers in Neurology, 2013
Motor dysfunction in Parkinson’s disease is believed to arise primarily from pathophysiology in the dorsal striatum and its related corticostriatal and thalamostriatal circuits during progressive dopamine denervation.
Jeff A Beeler, Giselle ePetzinger, Michael W. Jakowec   +2 more
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Working Memory Load, Automaticity, and Problem Solving in College Engineering Students: Two Applications

SAGE Open
The paper examined the relations among problem solving, automaticity, and working memory load (WML) by changing the difficulty level of task characteristics through two applications.
Yi Ding, Qian Wang, Ru-De Liu, Jolene Trimm, Jiayi Wang, Shu Feng, Wei Hong, Xian-Tong Yang   +7 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Ostracism Increases Automatic Aggression: The Role of Anger and Forgiveness

Frontiers in Psychology, 2019
While research on the “ostracism-aggression” link has focused on controlled processes in aggression, little effort has been devoted to examining the relation between ostracism and automatic aggression.
Denghao Zhang, Sen Li, Lei Shao, Andrew H. Hales, Kipling D. Williams, Fei Teng   +5 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Gesture–Speech Integration in Typical and Atypical Adolescent Readers

Frontiers in Psychology, 2022
This study investigated gesture–speech integration (GSI) among adolescents who are deaf or hard of hearing (DHH) and those with typical hearing. Thirty-eight adolescents (19 with hearing loss) performed a Stroop-like task in which they watched 120 short ...
Ru Yao, Connie Qun Guan, Elaine R. Smolen, Brian MacWhinney, Wanjin Meng, Laura M. Morett   +5 more
doaj   +1 more source