Results 51 to 60 of about 5,385 (262)

L’usage des automates interactifs dans les lieux publics

open access: yesCommunication, 2011
For the last twenty years, interactive information kiosks have become increasingly present in public places, providing transactional, orientational and informational services plus more didactic functions, particularly in Museology.
Daniel Thierry
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Automata Approach to XML Data Indexing

open access: yesInformation, 2018
The internal structure of XML documents can be viewed as a tree. Trees are among the fundamental and well-studied data structures in computer science. They express a hierarchical structure and are widely used in many applications.
Eliška Šestáková, Jan Janoušek
doaj   +1 more source

Regular omega-Languages with an Informative Right Congruence [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2018
A regular language is almost fully characterized by its right congruence relation. Indeed, a regular language can always be recognized by a DFA isomorphic to the automaton corresponding to its right congruence, henceforth the Rightcon automaton. The same
Dana Angluin, Dana Fisman
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Rich Ornaments and Delightful Engines: The Poetics of Failed Festivity and Figural Automation in William Shakespeare’s Titus Andronicus

open access: yesAnglica. An International Journal of English Studies, 2021
The present study focuses on the poetics of failed festivity in William Shakespeare’s Titus Andronicus, tracing analogies between early modern festival culture, in particular the Joyous Entry of the Renaissance prince into the city, and the machinery of ...
Agnieszka Żukowska
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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