Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Assessing the American public's preferences for reforms to teen driving licensure systems: a discrete choice experiment. [PDF]
Drabo EF, Michael JP, Ehsani JP.
europepmc +1 more source
Panel Discussion: Responsibility in Driving Safety - The Registry and the Driver. The Guild of St. Luke of Boston, Meeting-May14, 1967 [PDF]
Catholic Physicians\u27 Guild
core +2 more sources
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi +16 more
wiley +1 more source
A contemporary examination of the effect of driver training for reducing crash risk in novice adolescent drivers: protocol for the DRIVER study, a random assignment trial. [PDF]
Walshe EA +6 more
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
A multimodal approach for assessing the risk of cervical spine injury in low-speed rear-end collisions: kinematic and clinical responses. [PDF]
Lee HY +7 more
europepmc +1 more source
Pears v. State: An Improper Application of Alaska’s Current Law to Intoxicated Drivers [PDF]
Fishel, Alan
core +1 more source
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen +7 more
wiley +1 more source
Regulating ride-sourcing markets: Can minimum wage regulation protect drivers without disrupting the market? [PDF]
Ghasemi F +3 more
europepmc +1 more source

