Results 11 to 20 of about 2,143 (210)

Handgrip strength in older adults and driving aptitude [PDF]

open access: yesRevista Brasileira de Enfermagem, 2022
Objective: to analyze handgrip strength as a predictor of the inability to drive in older adults. Method: a cross-sectional study conducted in traffic clinics with 421 older adults in Curitiba-Paraná from January 2015 to December 2018.
Maria Helena Lenardt   +5 more
doaj   +1 more source

How to Apply Civil Liability to Users and Vehicles in Self-Driving Car Accidents [PDF]

open access: yesFaṣlnāmah-i Pizhūhish-i Huqūq-i Khuṣūṣī, 2023
Traditionally, the driver of the car is responsible for the damages caused by the accident. In self-driving and semi-autonomous cars, the term driver has either lost its meaning or has been diluted.
Nahid Parsa
doaj   +1 more source

The Roles and Performance of Professional Driving Instructors in Novice Driver Education

open access: yesSultan Qaboos University Medical Journal, 2017
This review article aimed to analyse existing literature regarding the roles and performance of professional driving instructors (PDIs) in novice driver education (DE).
Zulhaidi M. Jawi   +4 more
doaj   +1 more source

CHARACTERISTICS OF ELDERLY SUBMITTED TO DRIVER LICENSE TESTS

open access: yesCogitare Enfermagem, 2017
A quantitative, descriptive and retrospective study was undertaken to screen for the characteristics of elderly people who took the physical and mental aptitude test to get the Brazilian driver license. Data were collected from 1023 forms of elderly aged
Maria Helena Lenardt   +5 more
doaj   +1 more source

A complex suicide by vehicle assisted ligature strangulation and wrist-cutting

open access: yesEgyptian Journal of Forensic Sciences, 2016
Background: Complex suicide defines the type of suicide involving using more than one suicide methods to lead to death. Second method is used to escape from pain or to prevent failure of the first method. Here we present a case of unusual complex suicide
Ramazan Akçan   +3 more
doaj   +1 more source

Investigation of Recreational Vehicles Maneuverability on Forest Roads by Computer-Aided Driving Analysis

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2016
Forest road planning is a time-consuming and complicated process both because it requires environment-friendly road building, and due to the requirement to observe economic costs.
Mustafa Akgul   +4 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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