Results 71 to 80 of about 230,230 (352)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
The Incentive Effects of No Fault Automobile Insurance [PDF]
This paper presents a theoretical and empirical analysis of the effects of no fault automobile insurance on accident rates. As a mechanism for compensating the victims of automobile accidents, no fault has several important advantages over the tort ...
J. David Cummins +2 more
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Strict Liability in Cycling Laws to Ready the Roads for Environmentally Friendly Commuting [PDF]
, 2015 Because automobiles cause harmful effects on the environment, the United States should encourage bicycling as an alternative means of transportation to automobiles. Many Americans elect not to cycle as a means of transportation out of fear of a collision
Maker, Colleen
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Aging and Feminization: Implications for Future Travel Demands of the Elderly [PDF]
, 2003 An increasing proportion of the oldest-old (85+) population, combined with a pronounced abundance of older women relative to older men, characterize the demographic development of industrialized countries. Both, aging and feminization, strongly influence
Pitfield, David, Waldorf, Brigitte
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Driving automation: Learning from aviation about design philosophies [PDF]
, 2007 Full vehicle automation is predicted to be on British roads by 2030 (Walker et al., 2001). However, experience in aviation gives us some cause for concern for the 'drive-by-wire' car (Stanton and Marsden, 1996). Two different philosophies have emerged in
Harris, D, Stanton, NA, Young, MS
core +1 more source
Arthritis Care &Research, Accepted Article.Objective We developed a novel EHR sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk +16 more
wiley +1 more source
Журнал інженерних наукThe article emphasizes the importance and necessity of studying the behavior of automobile tires during operation in the starting mode, from the beginning of driving on “cold” tires to stabilizing its temperature and internal pressure. During this period,
Karpenko V. +3 more
doaj +1 more source
The role of the scale and the frequency bandwidth of steering wheel vibration on road surface recognition [PDF]
, 2006 Automobile drivers are regularly exposed to vibrational stimuli in their vehicle. Of the automobile subsystems, the steering wheel is one of the most important due to its role in controlling the vehicle.
Giacomin, J, Woo, Y J
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Arthritis Care &Research, Accepted Article.Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US Veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández +10 more
wiley +1 more source