Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
Advanced Science, EarlyView.The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source
Numerical and experimental investigation of CI engine parameters using palm biodiesel with diesel blends. [PDF]
Sci RepMusthafa B, Prabhahar M.
europepmc +1 more source
Autonomous Cars, Electric and Hybrid Cars, and Ridesharing: Perceptions vs. Reality
, 2018 Autonomous Cars, Electric and Hybrid Cars, and Ridesharing are all important new technologies in today\u27s society that can have potentially large impacts on the environment in the future.
Clarke, Charlie J. +2 more
core
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
Advanced Science, EarlyView.This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz +20 more
wiley +1 more source
Effect of mesh sizes on the vibrational and acoustic properties of stainless-steel wire mesh/glass fiber reinforced hybrid composite laminates. [PDF]
Sci RepSayyed J, Ramprasad A, Pai Y.
europepmc +1 more source
Technology assessment of future intercity passenger transportation systems. Volume 6: Impact assessment [PDF]
Consequences that might occur if certain technological developments take place in intercity transportation are described. These consequences are broad ranging, and include economic, environmental, social, institutional, energy-related, and transportation
core +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Data-driven demand analysis and design reliability study of critical components of complex products. [PDF]
PLoS OneMeng Z, Wang Z, Gao D, Lu W.
europepmc +1 more source
Advanced Science, EarlyView.This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang +9 more
wiley +1 more source