Results 121 to 130 of about 125,232 (287)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Ultrasound-Guided Stellate Ganglion Block Combined with Pharmacological Treatment for Rosacea: A Report of Two Cases

Patient Preference and Adherence
Changjian Gao, Fang Wang, Lulu Zhou, Weiwei Zhan, Rui Min Department of Anesthesiology, the Third Clinical Medical College of China Three Gorges University, Gezhouba Central Hospital of Sinopharm, Yichang, Hubei, 443002, People’s Republic of ...
Gao C, Wang F, Zhou L, Zhan W, Min R
doaj  

Thermal radiofrequency of the sphenopalatine ganglion in persistent idiopathic facial pain using a suprazygomatic approach: Case report. [PDF]

Interv Pain Med
Lasso Andrade FA, Gaviria Suarez G, Fernández Escobar A, Rivera Díaz RC, Achicanoy Puchana DM, Toro-López JE.   +5 more
europepmc   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Third-degree atrioventricular block after supraclavicular brachial plexus block: A case report. [PDF]

HeartRhythm Case Rep
Ramírez-Paesano CR, Colina-Vargas YA, Valente-Rivero A, Rivero-Novoa E, Jones-Segura M, Teresi L.   +5 more
europepmc   +1 more source

Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience

Advanced Science, EarlyView.
Atomically precise clusterzymes, engineered via atomic and ligand design, serve as programmable platforms for neuroscience applications. They demonstrate tailored biocatalysis for neuroinflammation, tunable optical properties for deep‐tissue bioimaging and 3D visualization, and enhanced charge transfer for brain–computer interfaces.
Si Sun, Di Liu, Sufei Zhou, Yang Wang, Hao Wang, Ziliang Zheng, Xiao‐Dong Zhang   +6 more
wiley   +1 more source

Temporal properties of direct current sensory block of the rat sciatic nerve using the C-fiber reflex. [PDF]

J Neural Eng
Green DB, Bender SA, Thakkar VS, Love TE, Hill HE, Kilgore KL, Bhadra N, Vrabec TL.   +7 more
europepmc   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

Cardiac Sympathetic Innervation and Ventricular Arrhythmias in Structural Heart Disease: Current Peripheral Neuromodulation Therapies and Emerging Therapeutic Targets. [PDF]

Arrhythm Electrophysiol Rev
Benabou L, Vaseghi M.
europepmc   +1 more source