Results 151 to 160 of about 782,534 (359)

Enzalutamide‐Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone‐Sensitive Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Expanding enzalutamide (ENZ) use in hormone‐sensitive prostate cancer (HSPC) faces resistance. Single‐cell profiling identifies therapy‐resistant STEAP4+ myofibroblastic cancer‐associated fibroblast (SETAP4+ myoCAF). These myoCAFs drive resistance via TFE3‐mediated autophagy and PCYT1A‐led phosphatidylcholine overproduction, creating a phospholipid ...
Wenhao Wang   +14 more
wiley   +1 more source

Underwater Instant Adhesive Hydrogel Interfaces for Robust Biosensing on Diverse Species

open access: yesAdvanced Science, EarlyView.
An instant underwater adhesion hydrogel interface is constructed via a universal and facile molecular entanglement engineering through a roll‐to‐roll scalable manufacturing protocol, achieving rapid and strong interfacial toughness over 230 J•m−2 within 10 s.
Xueyin Chen   +10 more
wiley   +1 more source

Partial Reprogramming in Senescent Schwann Cells Enhances Peripheral Nerve Regeneration via Restoration of Stress Granule Homeostasis

open access: yesAdvanced Science, EarlyView.
In this study, it is discovered that pathological accumulation of Runx2+ Schwann cell clusters​ during axonal regeneration is a key factor impairing nerve repair in aging. This pathology is associated with ​dysregulation of stress granule homeostasis.
Peilin Wang   +10 more
wiley   +1 more source

DORSOLATERAL PERIAQUEDUCTAL GREY MATTER IN THE CONTROL OF LARYNGEAL ACTIVITY AND SUBGLOTTIC PRESSURE IN SPONTANEOUSLY BREATHING ANAESTHETIZED RATS

open access: yesIBRO Neuroscience Reports, 2023
Marta González-García   +7 more
doaj   +1 more source

Artificial Nervous Systems

open access: yesAdvanced Science, EarlyView.
By drawing inspiration from biological neural hierarchies and the working mechanisms of plasticity, researchers have constructed a series of bionic devices, including sensory devices, synapse devices, and artificial neural systems. They committed to simulating and surpassing the biological information processing function, thereby realizing the ...
Lu Yang   +5 more
wiley   +1 more source

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