Results 111 to 120 of about 77,809 (262)

When do the symptoms of autonomic nervous system malfunction appear in patients with Parkinson’s disease?

open access: gold, 2014
Silvio R. De Luka   +4 more
openalex   +2 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

open access: yesAdvanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro   +6 more
wiley   +1 more source

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

open access: yesAdvanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao   +8 more
wiley   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen   +8 more
wiley   +1 more source

Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng   +10 more
wiley   +1 more source

Parameters of Autonomic Nervous System Dysfunction in Acute and Chronic Forms of Ischemic Heart Disease [PDF]

open access: diamond, 2017
А. С. Акулова   +4 more
openalex   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

open access: yesAdvanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi   +11 more
wiley   +1 more source

Curvy Surface Reconstruction

open access: yesAdvanced Science, EarlyView.
This review introduces the concept of “general curvy surface reconstruction,” which incorporates both geometric and physical dimensions, representing an upgrade over conventional geometric reconstruction that focuses solely on spatial relationships. Particular emphasis is placed on the emerging opportunities enabled by advanced measurement techniques ...
Chen Shang   +8 more
wiley   +1 more source

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