Results 61 to 70 of about 3,526,975 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Autonomic Communication Security in Sensor Networks [PDF]

open access: yes, 2006
The fact that sensor networks are deployed in wide dynamically changing environment and usually left unattended, calls for nomadic, diverse and autonomic behavior. The nature of security threats in such networks as well as the nature of the network itself raise additional security challenges, so new mechanisms and architectures must be designed to ...
Tassos Dimitriou, Ioannis Krontiris
openaire   +1 more source

Results of expert judgments on the faults and risks with Autosub3 and an analysis of its campaign to Pine Island Bay, Antarctica, 2009 [PDF]

open access: yes, 2009
Probabilistic risk assessment is a methodology that can be systematically applied to estimate the risk associated with the design and operation of complex systems.
Brito, Mario P., Griffiths, Gwyn
core   +1 more source

The Application of Principal Component Analysis (PCA) for the Study of the Spanish Tourist Demand

open access: yesQuaestiones Geographicae, 2018
The objective of this study is the characterisation of the Spanish autonomous communities as tourist destinations for Spanish trips, based on the activities carried out, using the principal component method.
González González María Jesús   +1 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

A Cross-Layer Architecture for Autonomic Communications [PDF]

open access: yes, 2006
Layered architectures are not sufficiently flexible to cope with the dynamics of wireless-dominated next-generation communications. Most existing architectures and approaches depend purely on local information and provide only poor and inaccurate information gathering at the global scale.
Mohammad Abdur Razzaque   +2 more
openaire   +2 more sources

Work solutions: improving cultural diversity and inclusion in the workplace [PDF]

open access: yes, 2014
Victoria would do well to make the most of its human resources and embrace newcomers who want to work no matter where they have been educated and gained their skills and experience.
Ethnic Communities' Council of Victoria
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Age-friendly communities : frequently asked questions

open access: yes, 2019
"September 2019."; Includes bibliographical referencesWhat is an age-friendly community? -- What are the build environment elements of an age-friendly community? -- What is aging in place? -- How can communities support aging in place?

core  

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