Results 51 to 60 of about 38,384 (267)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The constitutional guarantee of the provision of local Social Services in Spain: a comparative regional study

open access: yesRevista de Investigações Constitucionais
This article outlines the public architecture of social services in Spain from the perspective of the constitutional guarantee of the provision of local social services.
Maria Victòria Forns i Fernández   +1 more
doaj   +1 more source

Coordination of autonomic functionalities in communications networks

open access: yesCoRR, 2012
Future communication networks are expected to feature autonomic (or self-organizing) mechanisms to ease deployment (self-configuration), tune parameters automatically (self-optimization) and repair the network (self-healing). Self-organizing mechanisms have been designed as stand-alone entities, even though multiple mechanisms will run in parallel in ...
Combes, Richard   +2 more
openaire   +4 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Spanish regional offices in Brussels: are they vital for effective participation in the EU?

open access: yesRevista CIDOB d'Afers Internacionals, 2012
The agreements signed at the Conference for EU-Related Affairs (CARUE) in November 2004 represented an attempt to ensure the formal participation of Spain’s autonomous communities in the Council of the EU and its preparatory bodies.
Mirna Nouvilas Rodrigo
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

La distribución de competencias en materia energética: bloque de constitucionalidad y jurisprudencia constitucional

open access: yesRevista Vasca de Administración Pública, 2014
This paper analyses the allocation of competences between the state and the autonomous communities in the field of energy. First, it revisits the different legal bases of intervention that the constitution and the autonomy statutes recognise to the state
Xabier Arzoz Santisteban
doaj   +1 more source

The Application of Principal Component Analysis (PCA) for the Study of the Spanish Tourist Demand

open access: yesQuaestiones Geographicae, 2018
The objective of this study is the characterisation of the Spanish autonomous communities as tourist destinations for Spanish trips, based on the activities carried out, using the principal component method.
González González María Jesús   +1 more
doaj   +1 more source

From Organizational-Centric Engagement to Network-Centric Engagement: The Role of Autonomous Public Communities in a Mediated Public Policy Advocacy Network

open access: yesSocial Media + Society, 2021
In this study, we explore how a social movement organization ( Sunrise.org ) and its autonomous public community advocated for the Green New Deal on social media. An autonomous public community is a group of publics that initially connect with each other
Aimei Yang, Maureen Taylor
doaj   +1 more source

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