Results 41 to 50 of about 3,526,975 (302)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An Adaptive Hierarchical Approach to Lidar-based Autonomous Robotic Navigation
, 2018 Planetary missions are typically confined to navigationally safe environments, leaving areas of interest in rugged and/or hazardous terrain largely unexplored.
Brooks, Alexander J. -W. +5 more
core +1 more source
, 2004 S.A.F.E. is an acronym formed from the initial letters in the Value Statement of the Governor's Grant Program: Services are available and accessible in communities; Accountability of all systems, agencies, programs and individuals is provided; Funding is
Kansas Governor's S.A.F.E. Communities Program.
core +1 more source
Providing Social Scaffolding for Effective Agent Communities [PDF]
, 2013 AAAI Workshop on Autonomy, Delegation and Control: From Inter-agent to Groups, Edmonton, Canada, 2002This paper explores the general landscape of virtual communities and reflects upon their relevance to their agent community counterparts.
O'Hare, G. M. P. (Greg M. P.) +1 more
core +1 more source
Oñati Socio-Legal Series, 2016 Estamos asistiendo a un intenso debate en torno a la necesidad de generar un proceso regeneración democrática en el contexto actual de la crisis institucional y desafección política.
Reyes Pérez Alberdi
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Derechos y libertades y Estado de las Autonomías
Revista Vasca de Administración Pública, 2010 The descentralization of Spain which began in the constituant process meant a new territorial model of State, in-between a federal State and a centralized one.
M.ª Isabel Álvarez Vélez +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
« Etat composé » ou décomposé ?
L'Espace Politique, 2010 The Spanish Constitution of 1978 shares the power between the State and the Autonomous Communities. Over the past three decades, the principle of this "compound state" has become reality.
Nacima Baron
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source