Results 81 to 90 of about 175,264 (259)

Unsupervised Machine Learning for Networking: Techniques, Applications and Research Challenges

open access: yesIEEE Access, 2019
While machine learning and artificial intelligence have long been applied in networking research, the bulk of such works has focused on supervised learning.
Muhammad Usama   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

How many networks are we to manage? [PDF]

open access: yes
The continuous transformation of the industrial society into a service and knowledge society is accompanied by profound change of demand: Customer requests will increasingly focus on individual products, shorter delivery times and appropriate prices.
Roth, Steffen
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Towards goal-based autonomic networking [PDF]

open access: yes, 2009
The ability to quickly deploy and efficiently manage services is critical to the telecommunications industry. Currently, services are designed and managed by different teams with expertise over a wide range of concerns, from high-level business to low ...
Berglund, Åsa   +5 more
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Infrastructure-Wide and Intent-Based Networking Dataset for 5G-and-beyond AI-Driven Autonomous Networks

open access: yesSensors
In the era of Autonomous Networks (ANs), artificial intelligence (AI) plays a crucial role for their development in cellular networks, especially in 5G-and-beyond networks.
Jimena Andrade-Hoz   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Unmanned Surface Vessels in Marine Surveillance and Management: Advances in Communication, Navigation, Control, and Data-Driven Research

open access: yesJournal of Marine Science and Engineering
Unmanned Surface Vehicles (USVs) have emerged as vital tools in marine monitoring and management due to their high efficiency, low cost, and flexible deployment capabilities.
Zhichao Lv   +5 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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