Results 81 to 90 of about 7,018,157 (237)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Comparative System Analysis of Parabolic Trough Power Plants with DSG and Oil using Integrated Thermal Energy Storage [PDF]

open access: yes, 2011
In addition to the commercial parabolic trough power plants using synthetic oil, the direct steam generation (DSG) is one option for future trough plants.
Laing, Doerte   +6 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Photovoltaic sample-and-hold circuit enabling MPPT indoors for low-power systems [PDF]

open access: yes, 2012
Photovoltaic (PV) energy harvesting is commonly used to power autonomous devices, and maximum power point tracking (MPPT) is often used to optimize its efficiency. This paper describes an ultra low-power MPPT circuit with a novel sample-and-hold and cold-
Weddell, Alex S.   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Geothermal power plants : principles, applications and case studies /

open access: yes, 2005
Geothermal Power Plants: Principles, Applications and Case Studies is the latest book from Ron DiPippo, Professor Emeritus, University of Massachusetts Dartmouth. It is a single resource on all aspects of the utilization of geothermal energy for electric
DiPippo, Ronald.
core  

Multiple flashing in geothermal power plants

open access: yes
Geothermal-based flash steam power plants are promising systems for clean power generation. A comprehensive thermodynamic analysis through energy and exergy approaches is presented here to investigate the optimum flashing pressures for multistep plants ...

core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Solar chimney power plants: from theory to practice

open access: yes
Solar Chimney Power Plants: From Theory to Practice offers detailed information in one place, covering working principles, efficiency, performance-enhancing methods, experimental and theoretical studies, current application examples, techno-economic ...
Cüce, Erdem, Cüce, Pınar Mert
core   +1 more source

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