Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source
Facilitators and Barriers to Seeking Early Diagnosis and Treatment for Breast Cancer Among Patients Attending a Tertiary Care Hospital. [PDF]
CureusSingh P, Agrawal R.
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Quantitative perspectives of patients and healthcare professionals to inform the co-design of an mHealth application for knee osteoarthritis management. [PDF]
BMC Med Inform Decis MakErjavec K +3 more
europepmc +1 more source
Advanced Science, EarlyView.Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source
Fiscal decentralization, local government innovation preference, and enterprise technological innovation: Evidence from China. [PDF]
PLoS OneTu J.
europepmc +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
Advanced Science, EarlyView.We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
Ethical challenges in EEG neurofeedback: a systematic review of gaps, risks, and responsibilities. [PDF]
BMC Med EthicsÖlçüoğlu R, Yıldırım RV.
europepmc +1 more source
Financial decision-making power and mental well-being in older adults: a nationwide longitudinal cohort study in China. [PDF]
BMC GeriatrLi Y, Yang F.
europepmc +1 more source