Results 151 to 160 of about 5,550,027 (295)

Endoplasmic reticulum aggregation act as a nucleation site for autophagosome formation in an amyloid‐β model of Alzheimer’s disease [PDF]

, 2020
Raymond Chuen‐Chung Chang, Yuen‐Shan Ho, Sherry Sin Hang Yeung   +2 more
openalex   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Autophagosome formation [PDF]

Nature Immunology, 2014
openaire   +1 more source

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Dissection of Autophagosome Formation Using Apg5-Deficient Mouse Embryonic Stem Cells [PDF]

, 2001
Noboru Mizushima, Akitsugu Yamamoto, Masahiko Hatano, Yoshinori Kobayashi, Yukiko Kabeya, Kuninori Suzuki, Takeshi Tokuhisa, Yoshinori Ohsumi, Tamotsu Yoshimori   +8 more
openalex   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation

, 2008
Takashi Itoh, Naonobu Fujita, Eiko Kanno, Akitsugu Yamamoto, Tamotsu Yoshimori, Mitsunori Fukuda   +5 more
openalex   +2 more sources

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Spatio-temporal processes in autophagosome-lysosome fusion

Medical Review
Macroautophagy/autophagy is a lysosome-dependent degradation process involved in cellular energy metabolism, recycling and quality control. Autophagy is a highly dynamic and precisely regulated process, which contains four major steps: autophagic ...
Liu Shizuo, Yan Huan, Diao Jiajie, Zhang Shen, Zhong Qing   +4 more
doaj   +1 more source

Coronin-1a inhibits autophagosome formation around Mycobacterium tuberculosis-containing phagosomes and assists mycobacterial survival in macrophages [PDF]

, 2012
Shintaro Seto, Kunio Tsujimura, Yukio Koide   +2 more
openalex   +1 more source