Innate immunity shapes the persistent transmission of plant viruses by insect vectors
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley +1 more source
Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
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Porcine Epidemic Diarrhea Virus Infection Induces Autophagosome Formation but Inhibits Autolysosome Formation during Replication. [PDF]
Park JY, Ryu J, Hong EJ, Shin HJ.
europepmc +1 more source
ABSTRACT Ascidians are invertebrates that occupy a key phylogenetic position as a sister group of the vertebrates. The organization of their central nervous system (CNS), with cortex and medulla, indicates a plesiomorphic character of the gray and white matter of vertebrates, making this group of animals useful for studies of neurodegenerative events ...
Andressa de Abreu Mello +4 more
wiley +1 more source
Dissecting the role of the Atg12–Atg5-Atg16 complex during autophagosome formation [PDF]
Marta Walczak, Sascha Martens
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RHOD mediates ATG9A trafficking to promote autophagosome formation during autophagy in cancer. [PDF]
Wang S +7 more
europepmc +1 more source
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding +10 more
wiley +1 more source
ERdj8 governs the size of autophagosomes during the formation process [PDF]
Yo-hei Yamamoto +17 more
openalex +1 more source
Temporal dissection of the roles of Atg4 and ESCRT in autophagosome formation in yeast. [PDF]
Li H +10 more
europepmc +1 more source
TFG binds LC3C to regulate ULK1 localization and autophagosome formation. [PDF]
Carinci M +28 more
europepmc +1 more source

