Results 11 to 20 of about 308,405 (284)
Roles of autophagy and autophagy-related proteins in antifungal immunity [PDF]
Frontiers in Immunology, 2016 Autophagy was initially characterized as a process to digest cellular components, including damaged cell organelles or unused proteins. However, later studies showed that autophagy plays an important role to protect hosts from microbial infections ...
Masashi eKanayama +2 more
doaj +3 more sources
Degradation Mechanism of Autophagy-Related Proteins and Research Progress. [PDF]
Int J Mol Sci, 2022 In all eukaryotes, autophagy is the main pathway for nutrient recycling, which encapsulates parts of the cytoplasm and organelles in double-membrane vesicles, and then fuses with lysosomes/vacuoles to degrade them. Autophagy is a highly dynamic and relatively complex process influenced by multiple factors.
Zhou Y, Manghwar H, Hu W, Liu F.
europepmc +3 more sources
The nonautophagic functions of autophagy-related proteins. [PDF]
Autophagy, 2023 ATG: autophagy related; BECN1: beclin 1; cAMP: cyclic adenosine monophosphate; dsDNA: double-stranded DNA; EMT: epithelial-mesenchymal transition; IFN: interferon; ISCs: intestinal stem cells; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MAPK/JNK: mitogen-activated protein kinase/c-Jun N-terminal kinases; MTOR: mechanistic target of ...
Shang JN +6 more
europepmc +3 more sources
Non‐autophagic roles of autophagy‐related proteins [PDF]
EMBO reports, 2013 Autophagy and autophagy‐related processes are fundamentally important in human health and disease. These processes are viewed primarily as cellular degradative pathways that recycle macromolecules and dysfunctional or redundant organelles into amino acids, sugars and lipids, especially during starvation.
Suresh Subramani, Vivek Malhotra
openaire +2 more sources
Prognostic Value of Autophagy-related Proteins in Human Gastric Cancer. [PDF]
Cancer Manag Res, 2020 Autophagy-related proteins (ATG) play a crucial role in autophagy. Recently, the functions of autophagy in cancer have been gathering attention. However, the prognostic value of ATGs in gastric cancer (GC) has not been explored.The Kaplan-Meier plotter (KM plotter) online database was used to examine the value of ATGs gene expression levels in overall ...
Wu M, Chen B, Pan X, Su J.
europepmc +6 more sources
Autophagy-Related Pathways in Vesicular Unconventional Protein Secretion
Frontiers in Cell and Developmental Biology, 2022 Cellular proteins directed to the plasma membrane or released into the extracellular space can undergo a number of different pathways. Whereas the molecular mechanisms that underlie conventional ER-to-Golgi trafficking are well established, those associated with the unconventional protein secretion (UPS) pathways remain largely elusive.
Shin Hye Noh +3 more
openaire +4 more sources
Autophagy and Autophagy-Related Proteins in CNS Autoimmunity. [PDF]
Front Immunol, 2017 Autophagy comprises a heterogeneous group of cellular pathways that enables eukaryotic cells to deliver cytoplasmic constituents for lysosomal degradation, to recycle nutrients, and to survive during starvation. In addition to these primordial functions, autophagy has emerged as a key mechanism in orchestrating innate and adaptive immune responses and ...
Keller CW, Lünemann JD.
europepmc +5 more sources
Atg8: an autophagy-related ubiquitin-like protein family [PDF]
Genome Biology, 2011 Autophagy-related (Atg) proteins are eukaryotic factors participating in various stages of the autophagic process. Thus far 34 Atgs have been identified in yeast, including the key autophagic protein Atg8. The Atg8 gene family encodes ubiquitin-like proteins that share a similar structure consisting of two amino-terminal α helices and a ubiquitin-like ...
Shpilka, Tomer +3 more
openaire +2 more sources
Research progress on molecular mechanism of the interaction between autophagy and apoptosis [PDF]
Jichu yixue yu linchuang, 2021 Autophagy and apoptosis are two different physiological phenomena, however they are closely related in function. This paper introduces the classification and process of autophagy and apoptosis, and discusses the effects of some key regulatory proteins in
ZHANG Yang, SUN Wan-wan, LU Li-dan, FENG Xiao-ling
doaj
Upstream open reading frames mediate autophagy-related protein translation
Autophagy, 2022 Macroautophagy/autophagy, a highly conserved catabolic pathway that maintains proper cellular homeostasis is stringently regulated by numerous autophagy-related (Atg) proteins. Many studies have investigated autophagy regulation at the transcriptional level; however, relatively little is known about translational control.
Ying Yang +6 more
openaire +2 more sources