Results 211 to 220 of about 308,405 (284)

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy [PDF]

, 2018
Allavena, Giulia, Debellis, Doriana, Grimaldi, Benedetto, Joshi, Chetanchandra S, Marotta, Roberto, Mysorekar, Indira U   +5 more
core   +1 more source

Autophagy-related proteins measured in umbilical blood cord samples from human newborns: what can we learn from? [PDF]

Pediatr Res
Ginet V, Puyal J, Truttmann AC.
europepmc   +1 more source

Author's Response: The Difference in Expression of Autophagy Related Proteins in Lesional and Perilesional Skin in Adult Patients with Active and Stable Generalized Vitiligo - A Cross Sectional Pilot Study.

Indian J Dermatol, 2022
Yu H, Lin X, Huang Y, Cheng H, Seifert O.   +4 more
europepmc   +1 more source

Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. [PDF]

Sci Rep, 2020
He Z, Liu H, Moch H, Simon HU.
europepmc   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

Dead or Alive: Exploratory Analysis of Selected Apoptosis- and Autophagy-Related Proteins in Human Endometrial Stromal Cells of Fertile Females and Their Potential Role During Embryo Implantation. [PDF]

Int J Mol Sci
Scheliga I, Baston-Buest DM, Haramustek D, Knebel A, Kruessel JS, Bielfeld AP.   +5 more
europepmc   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

How Shall I Eat Thee? [PDF]

, 2007
Cuervo, Ana Maria, Dunn, Jr., William A., Klei, Ida van der, Klionsky, Daniel J., Levine, Beth, Seglen, Per O.   +5 more
core   +3 more sources

Knockdown of SMYD3 by RNA Interference Regulates the Expression of Autophagy-Related Proteins and Inhibits Bone Formation in Fluoride-Exposed Osteoblasts. [PDF]

Biol Trace Elem Res
Deng J, Zeng X, Zhang K, Zhang T, Dong Y, Zou J, Wu C, Li Y, Li F, Guan Z.   +9 more
europepmc   +1 more source