Results 271 to 280 of about 308,405 (284)

Spodoptera litura autophagy‐related protein 1 interacts with autophagy‐related protein 5 and enhances its degradation

Insect Molecular Biology, 2016
Abstract It is known that the autophagy‐related protein 1 (ATG1) plays critical roles in the regulation of autophagy in mammals and yeast, whereas the function of ATG1 in lepidopteran insects is not well elucidated.
N, Zhang, Y, Yang, H, Lu, Y, Xiang, X, Huang, R, Hu, Z, Chen, W, Yuan, R, Peng, J, Peng, H, Ai, K, Liu   +11 more
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Structural Studies of Autophagy-Related Proteins

2019
Information about the structure and dynamics of proteins is crucial for understanding their physiological functions as well as for the development of strategies to modulate these activities. In this chapter we will describe the work packages required to determine the three-dimensional structures of proteins involved in autophagy by using X-ray ...
Melanie, Schwarten, Oliver H, Weiergräber, Dušan, Petrović, Birgit, Strodel, Dieter, Willbold   +4 more
openaire   +2 more sources

Conformational Polymorphism in Autophagy-Related Protein GATE-16

Biochemistry, 2015
Autophagy is a fundamental homeostatic process in eukaryotic organisms, fulfilling essential roles in development and adaptation to stress. Among other factors, formation of autophagosomes critically depends on proteins of the Atg8 (autophagy-related protein 8) family, which are reversibly conjugated to membrane lipids.
Peixiang, Ma, Oliver, Schillinger, Melanie, Schwarten, Justin, Lecher, Rudolf, Hartmann, Matthias, Stoldt, Jeannine, Mohrlüder, Olujide, Olubiyi, Birgit, Strodel, Dieter, Willbold, Oliver H, Weiergräber   +10 more
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Abnormal expression of autophagy‐related proteins in immune thrombocytopenia

Scandinavian Journal of Immunology, 2020
AbstractAutophagy is a highly conserved protein degradation pathway that is essential for affecting some autoimmune diseases. Immune thrombocytopenia (ITP) is a common autoimmune disorder, and the complex dysregulation of cellular immunity has been observed; however, the relationship between autophagy‐related proteins and immune responses in ITP ...
Shu‐yan Liu, Xiao‐mei Zhang, Rui‐Jie Sun, Jing‐jing Zhu, Dai Yuan, Ning‐ning Shan   +5 more
openaire   +2 more sources

Nucleocytoplasmic expression of autophagy-related protein 7 in psoriasis

Menoufia Medical Journal, 2021
Objective The aim of this study was to evaluate the role of autophagy-related protein 7 (Atg7) in psoriasis. Background Despite psoriasis being a common skin disorder, the exact pathogenic mechanism of psoriasis is still not fully understood. Abnormal autophagy is now established to be associated with pathogenesis of some skin disorders.
AhmedE Tahoun, RehabM Samaka, MohammedA Basha, WafaaA Shehata   +3 more
openaire   +1 more source

Autophagy-related intrinsically disordered proteins in intra-nuclear compartments

Molecular BioSystems, 2016
Recent analyses indicated that autophagy can be regulatedviasome nuclear transcriptional networks and many important players in the autophagy and other forms of programmed cell death are known to be intrinsically disordered.
Na, Insung, Meng, Fanchi, Kurgan, Lukasz, Uversky, Vladimir N.   +3 more
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Autophagy-related protein 7 level in patients with ulcerative colitis

Scandinavian Journal of Gastroenterology, 2016
Sir,Pathogenesis of inflammatory bowel disease including ulcerative colitis (UC) is still not clear.
Kamran B, Lankarani, Masood, Sepehrimanesh, Seyedeh Fatemeh, Seghatoleslam, Seyed Ebrahim, Hoseini, Saeed, Ghavami   +4 more
openaire   +2 more sources

IMMUNOHISTOCHEMICAL ANALYSIS OF AUTOPHAGY-RELATED PROTEINS IN ODONTOGENIC KERATOCYSTS

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2020
Objective: To evaluate the immunoexpression of autophagy-related proteins (p62 and Atg7) in odontogenic keratocysts associated with Gorlin syndrome (SOKCs) and nonsyndromic odontogenic keratocysts (NSOKCs).Study design: The percentages of immunopositive cells (nuclear and cytoplasmic/membrane) for p62 and Atg7 in the epithelial component of 25 SOKCs ...
Fabianna da Conceiçao Dantas de MEDEIROS, Hellen Bandeira de Pontes SANTOS, Ana Luzia Araújo BATISTA, Roberta Barroso CAVALCANTE, Manuel Antonio GORDÓN-NÚÑEZ, Pollianna Muniz ALVES, Cassiano Francisco Weege NONAKA   +6 more
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Multilayered regulation of autophagy-related protein kinase in Cordyceps militaris

International Journal of Biological Macromolecules
Autophagy is a general eukaryotic mechanism for the degradation and recycling of macromolecules and organelles, whereby the ATG1-kinase complex plays a crucial initiator role. To understand the role of autophagy-related genes in the growth and development of the entomopathogenic parasitoid fungus Cordyceps militaris, we constructed ΔCmATG1 and ΔCmATG13
Yating, Wang, Ying, Wang, Bing, Li, Youran, Shao, Hongyu, Chen, Ming, Gong, Ruijing, Zhang, Yu, Liu, Wenjing, Chen, Nanyi, Li, Gen, Zou   +10 more
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Autophagy‐related protein expression in granulomatous skin diseases

The Journal of Dermatology, 2020
Shigeto Yanagihara, Hidenori Okazaki, Koji Sugawara, Toshiyuki Ozawa, Koji Sayama, Osamu Yamamoto, Daisuke Tsuruta, Kozo Nakai   +7 more
openaire   +2 more sources