Results 311 to 320 of about 528,011 (392)

Spatial and Temporal Progression of Neurodegeneration in Confirmed and Suspected TDP-43 Type C Pathology. [PDF]

Imaging Neurosci (Camb)
Stocks J, Behn J, Barbieri E, Mesulam MM.   +3 more
europepmc   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

From Fragile Lives to Forensic Truth: Multimodal Forensic Approaches to Pediatric Homicide and Suspect Death. [PDF]

Diagnostics (Basel)
Fragkou K, Ketsekioulafis I, Tousia A, Piagkou M, Bacopoulou F, Ferentinos P, Peyron PA, Baccino E, Martrille L, Papadodima S.   +9 more
europepmc   +1 more source

Atomic‐Level Engineering of Synthetic Receptors for Enhanced Virus Detection and Removal

Advanced Healthcare Materials, EarlyView.
Advanced computational techniques are employed to design and optimize computationally designed imprinted receptors (CIRs) for virus detection and removal. CIR‐conjugated piezoelectric sensor achieves highly sensitive virus detection in water and human serum. CIR‐integrated membranes remove 100% of pathogenic viruses from contaminated water.
Eda Akin, Ekin Sehit, Nastasia Sanda Moldovean‐Cioroianu, Sahana Tavaragondi, Sophia Slenczka, Roderich Süssmuth, Friedrich Jurk, Manuel van Gemmeren, Zeynep Altintas   +8 more
wiley   +1 more source

An Innovative “Tooth‐On‐Chip” Microfluidic Device Emulating the Structure and Physiology of the Dental Pulp Tissue

Advanced Healthcare Materials, EarlyView.
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale, Deborah Stanco, Roberta Visone, Bernd Stadlinger, Pierfrancesco Pagella, Marco Rasponi, Thimios A. Mitsiadis   +6 more
wiley   +1 more source

Child and Adolescent Suicide in the Broader Area of Athens, Greece: A 13-Year Retrospective Forensic Case-Series Analysis. [PDF]

Pediatr Rep
Fragkou K, Alexandri M, Dimitriou K, Tatsioni A, Bacopoulou F, Ferentinos P, Martrille L, Papadodima S.   +7 more
europepmc   +1 more source

Sentinel Panel of Districts: A new Platform for Health Monitoring and Evaluation in Tanzania [PDF]

, 2011
Idindili, Boniphace, Kabadi, Gregory, Manda, Constantine, Masanja, Honorati, Smithson, Paul   +4 more
core  

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, J. Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Psychological Autopsy in Adolescent Suicide: Evaluating Risk Factors and Research Methods. [PDF]

Psychiatry Investig
Lee S, Kyung S, Lee D.
europepmc   +1 more source