Results 91 to 100 of about 69,181 (263)
Gestión y Análisis de Políticas Públicas, 2015 Autores con participación en este número.
openaire +2 more sources
Advanced Science, EarlyView.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
Concepción de los derechos de autor relativos a la música: análisis desde su fundamentación
Pensamiento AmericanoIntroducción: El presente artículo de investigación aborda la temática de los derechos de autor en la industria musical por medio de la conceptualización de diversas nociones que componen los espectros de los derechos de propiedad intelectual.
María Fernanda Jaimes Melgarejo +3 more
doaj +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Advanced Science, EarlyView.Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He +10 more
wiley +1 more source
Recolha de circunstâncias: o diário como álbum
Literatura: Teoría, Historia, CríticaO artigo analisa a caracterização do gênero diarístico como álbum, a partir da diferenciação mallarmaica entre Livro e Álbum, da abordagem de Roland Barthes sobre o tema e do caso específico representado pela trilogia Os diários de Emilio Renzi, de ...
Júlio Pimentel Pinto
doaj +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Advanced Science, EarlyView.Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay
Advanced Science, EarlyView.This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao +6 more
wiley +1 more source
Advanced Science, EarlyView.This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu +12 more
wiley +1 more source
O narrador recusado por Saramago
Estudos Semióticos, 2016 Este artigo foi motivado por duas declarações do escritor português José Saramago, nas quais ele rejeita a existência de um narrador não identificado com o autor.
José Leite Jr
doaj