Results 141 to 150 of about 3,656,678 (311)
Advanced Science, EarlyView.Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu +11 more
wiley +1 more source
Autore, autore implicito e autotraduzione
, 2023 La ormai ‘storica’ dichiarazione della morte dell’autore viene esaminata alla luce del fenomeno moderno e antico dell’autotraduzione. Riguardo l’emergere nel testo della funzione-autore, vengono individuati (accanto alle scontate divergenze) elementi di solidarietà sia fra la pratica autotraduttiva contemporanea e quella quattrocentesca, sia per quel ...
openaire +1 more source
Advanced Science, EarlyView.This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
Ciencia y AgriculturaLas infecciones de sitio quirúrgico (ISQ) son un tipo de afecciones asociadas a la atención en salud (IAAS) que ocurre después de una intervención quirúrgica, en una zona del cuerpo donde se llevó a cabo una incisión, implicando piel, tejidos y órganos,
MELISA DANIELA MUNEVAR ROMERO +4 more
doaj +2 more sources
The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation
Advanced Science, EarlyView.ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley +1 more source
Advanced Science, EarlyView.The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng +5 more
wiley +1 more source
Movimiento CientíficoIntroducción: El fitness muscular, específicamente la fuerza prensil, se ha identificado como un indicador relevante de salud y condición física en mujeres jóvenes.
Ariel de Jesus Cañas Leyva +3 more
doaj
Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits
Advanced Science, EarlyView.Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu +16 more
wiley +1 more source
ELABORACIÓN DE UN PROTOCOLO DE PLASTINACIÓN PARA LA CONSERVACIÓN DE UN CORAZÓN DE BOVINO
Ciencia y AgriculturaSe presenta un protocolo alternativo y económico para plastinar piezas anatómicas, centrado en un corazón bovino como muestra. Se enfatiza la importancia de la Anatomía Veterinaria y los riesgos asociados al uso de formol en la conservación de tejidos ...
MELISA DANIELA MUNEVAR ROMERO +3 more
doaj