Results 101 to 110 of about 62,954 (311)

N‐of‐1 trials in clinical research: Methodological foundations, statistical approaches and implementation challenges

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho   +5 more
wiley   +1 more source

Two-dimensional autoregressive model in a steganographic method based on the direct spread spectrum

open access: yesБезопасность информационных технологий, 2016
Considered steganographic method of information security based on the direct spreading. Possibility of two-dimensional autoregressive model application in this steganographic method is investigated.
Rodion Khamzaevich Baltaev   +1 more
doaj  

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel   +12 more
wiley   +1 more source

Does ESG Investing Pay off? Comparing the Performance of ESG and Traditional ETFs Across European and US Markets

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Investors have long recognized the importance of firms in promoting sustainability, leading to the rise of socially responsible investment (SRI). Specifically, there is a growing preference for exchange‐traded funds (ETFs) that prioritize environmental, social, and governance (ESG) principles.
Sandra Tenorio‐Salgueiro   +3 more
wiley   +1 more source

On subset least squares estimation and prediction in vector autoregressive models with exogenous variables

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract We establish the consistency and the asymptotic distribution of the least squares estimators of the coefficients of a subset vector autoregressive process with exogenous variables (VARX). Using a martingale central limit theorem, we derive the asymptotic normal distribution of the estimators. Diagnostic checking is discussed using kernel‐based
Pierre Duchesne   +2 more
wiley   +1 more source

Random finite element analysis on ground subsidence caused by tunnel excavation in karst regions with spatial variable soil

open access: yesDeep Underground Science and Engineering, EarlyView.
This study investigates ground subsidence during tunnel excavation in karst areas, highlighting the combined effects of karst cave proximity, cave size, and soil spatial variability. Findings suggest that shorter cave distances and larger cave sizes increase subsidence variability, and a modified Peck formula is proposed for more accurate subsidence ...
Zhenghong Su   +4 more
wiley   +1 more source

Nested AutoRegressive Models

open access: yes
AutoRegressive (AR) models have demonstrated competitive performance in image generation, achieving results comparable to those of diffusion models. However, their token-by-token image generation mechanism remains computationally intensive and existing solutions such as VAR often lead to limited sample diversity.
Wu, Hongyu   +3 more
openaire   +2 more sources

Does biotic resistance govern forest invasions by bark and ambrosia beetles?

open access: yesEcography, EarlyView.
The theory of biotic resistance states that community diversity promotes resistance to biological invasions. This theory has been widely explored for its ability to explain variation in habitat invasibility to non‐native plant species and while the theory holds in some systems, it does not in others.
Jiří Trombik   +4 more
wiley   +1 more source

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