Results 11 to 20 of about 1,332 (157)

Cognitive function in late‐stage HFpEF patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1323-1330, December 1, 2022., 2022
Abstract Objectives This study evaluates the impact of transcatheter tricuspid valve interventions (TTVI) on cognitive function (CF), quality of life (QOL), and exercise capacity in late‐stage heart failure with preserved ejection fraction (HFpEF) and relevant tricuspid regurgitation (TR).
Muhammed Gerçek, Anca A. Irimie, Mustafa Gerçek, Henrik Fox, Vera Fortmeier, Tanja K. Rudolph, Volker Rudolph, Kai P. Friedrichs   +7 more
wiley   +1 more source

Revising immune cell coordination: Origins and importance of single‐cell variation

European Journal of Immunology, Volume 52, Issue 12, Page 1889-1897, December 2022., 2022
Single immune cell coordination relies on heterogeneous cellular decision‐making subject to noise, stochastic inputs, and deterministic cell fates. To coordinate collective, population‐wide immune responses, single immune cells are part of complex signaling networks, in which cells rely on various communication strategies.
Laura C. Van Eyndhoven, Jurjen Tel
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

Construction of hybrid 1D‐0D networks for efficient and accurate blood flow simulations

International Journal for Numerical Methods in Fluids, Volume 95, Issue 2, Page 262-312, February 2023., 2023
A set of coupling equations to appropriately couple nonlinear 1D and lumped‐parameter (0D) models for blood flow in compliant vessels is defined. Then, a methodology for the high‐order numerical coupling between 1D and 0D vessels through hybrid junctions is proposed.
Beatrice Ghitti, Pablo J. Blanco, Eleuterio F. Toro, Lucas O. Müller   +3 more
wiley   +1 more source

Study on the efficacy of compound porcine cerebroside and ganglioside injection in patients with ischemic stroke: A randomized, single‐center, open‐label, prospective study

Ibrain, EarlyView., 2023
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen, Xia Zhang, Hai‐Qing Zhang, Zhong Luo, Xue‐Jiao Zhou, Tao Liang, Fei Yang, Jun Zhang, Zu‐Cai Xu   +8 more
wiley   +1 more source

Placental pathology and neonatal encephalopathy

International Journal of Gynecology &Obstetrics, Volume 160, Issue 1, Page 22-27, January 2023., 2023
Abstract Neonatal encephalopathy (NE) is an important cause of neonatal morbidity and mortality worldwide; however, there remain gaps in our knowledge about its pathogenesis. The placenta has been implicated in the pathogenesis of this disease but conclusive evidence related to the placental factors that influence it is sparse.
Aine Fox, Emma Doyle, Michael Geary, Breda Hayes   +3 more
wiley   +1 more source

Cerebral vascular function following the acute consumption of caffeinated artificially- and sugar sweetened soft drinks in healthy adults

Frontiers in Human Neuroscience, 2022
Chronic consumption of sugar- and artificially-sweetened beverages (SSB and ASB) are associated with an increased risk of stroke but it is unclear how acute consumption influences cerebral vascular function.Purpose: We hypothesized that: (1) acute ...
Emma L. Reed, Morgan L. Worley, Paul J. Kueck, Leonard D. Pietrafasa, Zachary J. Schlader, Blair D. Johnson, Blair D. Johnson   +6 more
doaj   +1 more source

Keeping development on time: Insights into post‐transcriptional mechanisms driving oscillatory gene expression during vertebrate segmentation

WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023
Genetic oscillators play crucial roles in development. The hairy/Enhancer of split gene family (Hes/her) undergo cell‐autonomous genetic oscillations to regulate the timing of vertebrate segmentation and neural cell proliferation and differentiation. mRNA stability and translation are tightly regulated to maintain oscillatory expression.
Monica C. Blatnik, Thomas L. Gallagher, Sharon L. Amacher   +2 more
wiley   +1 more source

Vascular Reactivity to Hypercapnia Is Impaired in the Cerebral and Retinal Vasculature in the Acute Phase After Experimental Subarachnoid Hemorrhage

Frontiers in Neurology, 2022
Objective: Impaired cerebral blood flow (CBF) regulation, such as reduced reactivity to hypercapnia, contributes to the pathophysiology after aneurysmal subarachnoid hemorrhage (SAH), but temporal dynamics in the acute phase are unknown.
Laura Warner, Annika Bach-Hagemann, Walid Albanna, Hans Clusmann, Gerrit A. Schubert, Gerrit A. Schubert, Ute Lindauer, Ute Lindauer, Catharina Conzen-Dilger   +8 more
doaj   +1 more source

Neonatal cerebrovascular autoregulation [PDF]

Pediatric Research, 2018
Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral blood flow (CBF) relatively constant across changes in cerebral perfusion pressure (CPP). Cerebral vasoreactivity refers to the vasoconstriction and vasodilation that occur during fluctuations in arterial blood pressure (ABP) to maintain autoregulation.
Rhee, Christopher J, Da Costa, Cristine Sortica, Austin, Topun, Brady, Ken M, Czosnyka, Marek, Lee, Jennifer K   +5 more
openaire   +3 more sources