Results 311 to 320 of about 103,155 (374)

Supramolecular Autoregulation

Journal of the American Chemical Society, 2013
Enzyme activity in biological systems is often governed by control mechanisms in which the catalytic properties are made sensitive or insensitive to differences in enzyme or substrate concentration. Here, we report the first supramolecular system where the catalytic activity is made concentration independent through the use of newly designed inhibitor ...
Rodriguez Llansola, F., Meijer, E.W.
openaire   +3 more sources

Cerebral Oxygenation and Autoregulation in Preterm Infants (Early NIRS Study).

Jornal de Pediatria, 2020
OBJECTIVE To determine if decreased cerebral oxygenation or altered cerebral autoregulation as measured by near-infrared spectroscopy (NIRS) in the first 96 postnatal hours is associated with an increased risk of death or severe neuroradiographic ...
V. Chock, Soo Hyun Kwon, N. Ambalavanan, B. Batton, L. Nelin, L. Chalak, Lu Tian, K. V. van Meurs   +7 more
semanticscholar   +1 more source

Personalized Blood Pressure Management During Cardiac Surgery With Cerebral Autoregulation Monitoring: A Randomized Trial.

Seminars in Thoracic and Cardiovascular Surgery, 2020
The purpose of this study was to determine if setting mean arterial pressure (MAP) targets during cardiopulmonary bypass (CPB) based on individualized cerebral autoregulation data reduces the frequency of neurological complications compared with usual ...
C. Hogue, Charles H. Brown, D. Hori, M. Ono, Yohei Nomura, Lauren C. Balmert, N. Srdanovic, J. Grafman, K. Brady   +8 more
semanticscholar   +1 more source

Monitoring of cerebral blood flow autoregulation: physiologic basis, measurement, and clinical implications.

British Journal of Anaesthesia
Cerebral blood flow (CBF) autoregulation is the physiologic process whereby blood supply to the brain is kept constant over a range of cerebral perfusion pressures ensuring a constant supply of metabolic substrate.
E. Vu, Charles H Brown, K. Brady, Charles W. Hogue   +3 more
semanticscholar   +1 more source

To Autoregulate or Not to Autoregulate—That is No Longer the Question

Seminars in Pediatric Neurology, 2009
In the late 1970s, high cerebral blood flow was perceived as a cause of intracranial hemorrhage in the preterm infant. Intracranial hemorrhage was diagnosed by computed tomography and ultrasound found to be frequent not only in babies who died. Hemorrhage was soon linked to cerebral palsy in survivors. The analogy was hypertensive hemorrhagic stroke in
openaire   +3 more sources

THE AUTOREGULATION OF THE MICROCIRCULATION

Acta Medica Scandinavica, 1975
Abstract. The paper reviews August Krogh's contribution to capillary physiology stressing his formulation of useful new concepts such as “tissue cylinder model”, capillary intermittency and the intimate matching of capillary perfusion and cellular metabolism.
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Assessment of renal autoregulation

American Journal of Physiology-Renal Physiology, 2007
The kidney displays highly efficient autoregulation so that under steady-state conditions renal blood flow (RBF) is independent of blood pressure over a wide range of pressure. Autoregulation occurs in the preglomerular microcirculation and is mediated by two, perhaps three, mechanisms.
William A, Cupples, Branko, Braam
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Cerebral autoregulation and ageing

Journal of Clinical Neuroscience, 2005
Little is known about the effects of ageing on cerebral autoregulation (CA). To examine the relationship between age and CA in adults, we conducted a prospective study using a non-invasive protocol without external stimuli. We studied 32 subjects, aged 23-68 years. They were assigned to a young group (28+/-5 years) and an old group (54+/-8 years).
Yam, A T, Lang, E W, Lagopoulos, Jim, Yip, K, Griffith, J, Mudaliar, Y, Dorsch, N W   +6 more
openaire   +3 more sources

Heterogeneity and Variability in Pressure Autoregulation of Organ Blood Flow: Lessons Learned Over 100+ Years

Critical Care Medicine, 2019
Objectives: Pressure autoregulation is an organ’s intrinsic ability to maintain blood flow despite changes in perfusion pressure. The purpose of this review is to discuss autoregulation’s heterogeneity among different organs and variability under ...
L. Meng, Yingwei Wang, Lina Zhang, D. McDonagh   +3 more
semanticscholar   +1 more source

Mitotic Autoregulation: a Reply

Nature, 1970
THE essence of my model, of which the paradigm is Bertalanffy's model of constant cell size in microorganisms1, is that the geometry of the population is critical with important implications for organ growth characteristics, especially in development.
openaire   +2 more sources