Results 41 to 50 of about 1,332 (157)

The angiotensin II type I receptor contributes to impaired cerebral blood flow autoregulation caused by placental ischemia in pregnant rats

Biology of Sex Differences, 2019
Background Placental ischemia and hypertension, characteristic features of preeclampsia, are associated with impaired cerebral blood flow (CBF) autoregulation and cerebral edema.
Junie P. Warrington, Fan Fan, Jeremy Duncan, Mark W. Cunningham, Babette B. LaMarca, Ralf Dechend, Gerd Wallukat, Richard J. Roman, Heather A. Drummond, Joey P. Granger, Michael J. Ryan   +10 more
doaj   +1 more source

Static autoregulation in humans [PDF]

Journal of Cerebral Blood Flow & Metabolism
A recent publication in JCBFM, “Static autoregulation in humans” gives rise to critical comments. Autoregulation of cerebral blood flow implies that flow is rather constant within a certain blood pressure (BP) range with a lower and an upper pressure limit.
Olaf B Paulson, Svend Strandgaard, Jes Olesen, Jean-Claude Baron   +3 more
openaire   +2 more sources

Cerebral autoregulation monitoring in neonates and infants after cardiac surgery with cardiopulmonary bypass - comparison of single ventricle and biventricular physiology

Frontiers in Pediatrics
IntroductionCardiopulmonary bypass surgery can lead to impaired cerebral autoregulation with the risk for ischemia, hemorrhage and delirium. In particular, infants with single ventricle physiology have altered hemodynamics with persistent veno-arterial ...
Marcel Methner, Bernadett Schwaneberg, Berit Wikidal, Simon Schmid, Julian Zipfel, Maximilian Iller, Martin U. Schuhmann, Yordan H. Georgiev, Harry Magunia, Rafal Berger, Christian Schlensak, Johannes Nordmeyer, Felix Neunhoeffer   +12 more
doaj   +1 more source

Cerebral Blood Flow Deviations in Critically Ill Patients: Potential Insult Contributing to Ischemic and Hyperemic Injury

Frontiers in Medicine, 2021
Background: Ischemic and hyperemic injury have emerged as biologic mechanisms that contribute to cognitive impairment in critically ill patients. Spontaneous deviations in cerebral blood flow (CBF) beyond ischemic and hyperemic thresholds may represent ...
Marat Slessarev, Marat Slessarev, Marat Slessarev, Ossama Mahmoud, Christopher W. McIntyre, Christopher W. McIntyre, Christopher G. Ellis, Christopher G. Ellis   +7 more
doaj   +1 more source

Cerebral Blood Flow Autoregulation in Offspring From Experimentally Preeclamptic Rats and the Effect of Age

Frontiers in Physiology, 2022
Preeclampsia is a hypertensive disorder of pregnancy that causes significant, long term cardiovascular effects for both the mother and offspring. A previous study demonstrated that middle cerebral arteries in offspring from an experimental rat model of ...
Emmett E. Whitaker, Emmett E. Whitaker, Emmett E. Whitaker, Abbie C. Johnson, Sarah M. Tremble, Conor McGinn, Nicole DeLance, Marilyn J. Cipolla, Marilyn J. Cipolla, Marilyn J. Cipolla, Marilyn J. Cipolla   +10 more
doaj   +1 more source

Tristetraprolin affects invasion‐associated genes expression and cell motility in triple‐negative breast cancer model

Cytoskeleton, EarlyView.
Abstract Tristetraprolin (TTP) is an RNA‐binding protein that negatively regulates its target mRNAs and has been shown to inhibit tumor progression and invasion. Tumor invasion requires precise regulation of cytoskeletal components, and dysregulation of cytoskeleton‐associated genes can significantly alter cell motility and invasive capability. Several
Anastasiia Hubiernatorova, Josef Novak, Michaela Vaskovicova, David Sekac, Serhii Kropyvko, Zdenek Hodny   +5 more
wiley   +1 more source

Cerebral Autoregulation Is Disrupted Following a Season of Contact Sports Participation

Frontiers in Neurology, 2018
Repetitive subconcussive head impacts across a season of contact sports participation are associated with a number of deficits in brain function.
Alexander D. Wright, Alexander D. Wright, Alexander D. Wright, Alexander D. Wright, Jonathan D. Smirl, Kelsey Bryk, Kelsey Bryk, Sarah Fraser, Michael Jakovac, Paul van Donkelaar   +9 more
doaj   +1 more source

Autoregulation in the Biosynthesis of Ribosomes [PDF]

Molecular and Cellular Biology, 2003
The synthesis of ribosomes in Saccharomyces cerevisiae consumes a prodigious amount of the cell's resources and, consequently, is tightly regulated. The rate of ribosome synthesis responds not only to nutritional cues but also to signals dependent on other macromolecular pathways of the cell, e.g., a defect in the secretory pathway leads to severe ...
Yu Zhao, Jung-Hoon Sohn, Jonathan R. Warner   +2 more
openaire   +3 more sources

Increased impairment of cerebral autoregulation in COVID-19 associated pulmonary failure requiring extracorporeal membrane oxygenation

Frontiers in Medicine
IntroductionCerebrovascular complications are feared but also commonly reported in patients with COVID-19 requiring extracorporeal membrane oxygenation (ECMO) support therapy.
Marcus Thudium, Jochen Kappler, Maximilian J. G. Oremek, Stefan Felix Ehrentraut, Evgeniya Kornilov, Milka Marinova, Christian Putensen, Martin Soehle, Jens-Christian Schewe, Jens-Christian Schewe   +9 more
doaj   +1 more source

Regulation of Tubulin Gene Expression: From Isotype Identity to Functional Specialization

Frontiers in Cell and Developmental Biology, 2022
Genomes of higher eukaryotes encode a large tubulin gene superfamily consisting of at least six α and six β-tubulin isotypes. While some α and β-tubulin isotypes are ubiquitously expressed, others are cell-type specific.
Ivana Gasic
doaj   +1 more source