Results 71 to 80 of about 1,332 (157)

Multifocal Infarctions as Manifestation of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare small vessel disease caused by a pathogenic variant in the NOTCH3 gene. We present a unique case of acute multifocal infarcts in a 51‐year‐old female following a syncopal event, prompting investigations and a first diagnosis of ...
Spiro Menounos, Adarsh George, Ke Sun, Dandan Zhao, Lydia Ting, Daniel Guilfoyle, Katie Yin   +6 more
wiley   +1 more source

Retinal Microcirculation Measurements in Response to Endurance Exercises Analysed by Adaptive Optics Retinal Camera

Diagnostics
This study aimed to precisely investigate the effects of intensive physical exercise on retinal microvascular regulation in healthy volunteers through adaptive optics retinal camera (AO) measurement.
Maria Anna Żmijewska, Zbigniew M. Wawrzyniak, Maciej Janiszewski, Anna Zaleska-Żmijewska   +3 more
doaj   +1 more source

Acidic C-terminal domains autoregulate the RNA chaperone Hfq

eLife, 2017
The RNA chaperone Hfq is an Sm protein that facilitates base pairing between bacterial small RNAs (sRNAs) and mRNAs involved in stress response and pathogenesis. Hfq possesses an intrinsically disordered C-terminal domain (CTD) that may tune the function
Andrew Santiago-Frangos, Jeliazko R Jeliazkov, Jeffrey J Gray, Sarah A Woodson   +3 more
doaj   +1 more source

Tripartite Symbiosis Between Legumes, Arbuscular Mycorrhizal Fungi and Nitrogen Fixing Rhizobia: Interactions and Regulation

Plant, Cell &Environment, EarlyView.
ABSTRACT Legume plants can interact with nitrogen‐fixing rhizobia bacteria and arbuscular mycorrhizal fungi (AMF) simultaneously, forming a tripartite symbiotic association. Co‐inoculation studies performed on a variety of legumes have shown that rhizobia and AMF influence each other when they co‐occur in tripartite association and affect host plant ...
Polyxeni Gorgia, Daniela Tsikou
wiley   +1 more source

New Integrative Vectors Increase Agrobacterium rhizogenes Transformation and Help Characterise Roles for Soybean GmTML Gene Family Members

Plant, Cell &Environment, EarlyView.
ABSTRACT Hairy‐root transformation is widely used to generate transgenic plant roots for genetic functional characterisation studies. However, transformation efficiency can be limited, largely due to the use of binary vectors. Here, we report on the development of novel integrative vectors that significantly increase the transformation efficiency of ...
Huanan Su, Mengbai Zhang, Estelle B. Grundy, Brett J. Ferguson   +3 more
wiley   +1 more source

Cardiac output‐mediated regulation of cerebral blood flow during exercise: Clinical perspectives on the indirect impact of muscle metaboreflex

Experimental Physiology, EarlyView.
Abstract The muscle metaboreflex stimulates the elevation of arterial blood pressure, aiming to rectify the oxygen deficit by enhancing oxygen delivery to support muscle activity. Moreover, activating the muscle metaboreflex significantly increases cardiac output (CO) by increasing factors such as heart rate, ventricular contractility, preload, stroke ...
Shigehiko Ogoh
wiley   +1 more source

Feasibility of superimposed supine cycling and lower body negative pressure as an effective means of prolonging exercise tolerance in individuals experiencing persisting post‐concussive symptoms: Preliminary results

Experimental Physiology, EarlyView.
Abstract To examine the feasibility, utility and safety of superimposed lower body negative pressure (LBNP) and tilt during supine cycling in individuals suffering from persisting post‐concussive symptoms (PPCS). Eleven individuals aged 17–31 (6 females/5 males) participated in two randomized separate visits, 1 week apart.
Raelyn Javra, Joel S. Burma, Nathan E. Johnson, Jonathan D. Smirl   +3 more
wiley   +1 more source

Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels

Frontiers in Integrative Neuroscience, 2013
Serotonergic neurons project to virtually all regions of the CNS and are consequently involved in many critical physiological functions such as mood, sexual behavior, feeding, sleep/wake cycle, memory, cognition, blood pressure regulation, breathing and ...
Takashi eMaejima, Olivia Andrea Masseck, Melanie Danelle Mark, Stefan eHerlitze   +3 more
doaj   +1 more source

Effects of the angle of head‐down tilt on dynamic cerebral autoregulation during combined exposure to cephalad fluid shift and mild hypercapnia

Experimental Physiology, EarlyView.
Abstract Astronauts experience combined exposure to a cephalad fluid shift and mild hypercapnia during space missions, potentially contributing to health problems. Such combined exposure may weaken dynamic cerebral autoregulation. The magnitude of cephalad fluid shift varies between individuals, and dynamic cerebral autoregulation may be affected more ...
Tomokazu Kato, Yojiro Ogawa, Ken‐ichi Iwasaki   +2 more
wiley   +1 more source

The ntrPR Operon of Sinorhizobium meliloti Is Organized and Functions as a Toxin-Antitoxin Module

Molecular Plant-Microbe Interactions, 2006
The chromosomal ntrPR operon of Sinorhizobium meliloti encodes a protein pair that forms a toxin-antitoxin (TA) module, the first characterized functional TA system in Rhizobiaceae. Similarly to other bacterial TA systems, the toxin gene ntrR is preceded
Monica Bodogai, Szilamér Ferenczi, Denys Bashtovyy, Paul Miclea, Péter Papp, Ilona Dusha   +5 more
doaj   +1 more source