Results 71 to 80 of about 98,858 (333)

Sheep femoral artery occlusion is well tolerated and does not result in ischemia

Animal Models and Experimental Medicine, EarlyView.
Left femoral artery occlusion (yellow arrows) can be seen shortly after the lateral femoral circumflex artery origin, with distal arterial reconstitution. Sheep with femoral artery occlusion showed no change in pain scores nor mobility, thus making them an appropriate model for novel small diameter femoral artery graft studies. Abstract Objective Sheep
Timothy Shiraev, Ziyu Wang, Lakshay Seth, Lisa Partel, Innes K. Wise, Hugh Paterson, John O'Sullivan, Sean Lal, Anthony S. Weiss, Paul Bannon, Robert D. Hume   +10 more
wiley   +1 more source

Under-dominance constrains the evolution of negative autoregulation in diploids [PDF]

, 2013
Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change.
Pomiankowski, A, Reuter, M, Seymour, RM, Stewart, AJ   +3 more
core  

Linking Stochastic Dynamics to Population Distribution: An Analytical Framework of Gene Expression [PDF]

, 2006
We present an analytical framework describing the steady-state distribution of protein concentration in live cells, considering that protein production occurs in random bursts with an exponentially distributed number of molecules.
Cai, Long, Friedman, Nir, Xie, X. Sunney
core   +1 more source

Impaired cerebral autoregulation is associated with brain dysfunction in patients with sepsis

Critical Care, 2018
BackgroundSepsis-associated brain dysfunction (SABD) is associated with high morbidity and mortality. The pathophysiology of SABD is multifactorial.
I. Crippa, C. Subirà, J. Vincent, R. Fernandez, S. Hernández, F. Cavicchi, J. Creteur, F. Taccone   +7 more
semanticscholar   +1 more source

The Predictive Value of Quantitative Flow Ratio and Its Derived Angiographic Microvascular Resistance for Restenosis Following Drug‐Coated Balloon Angioplasty

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Initially, drug‐coated balloon (DCB) angioplasty was primarily employed for in‐stent restenosis (ISR) treatment. Over time, its indications have broadened to include de novo small‐vessel lesions and bifurcation lesions. However, there is a lack of effective strategies to reduce restenosis rates post‐DCB angioplasty.
Chenhang Wang, Li Chen, Xiaoyong Xu
wiley   +1 more source

Autoregulation in the Biosynthesis of Ribosomes [PDF]

Molecular and Cellular Biology, 2003
The synthesis of ribosomes in Saccharomyces cerevisiae consumes a prodigious amount of the cell's resources and, consequently, is tightly regulated. The rate of ribosome synthesis responds not only to nutritional cues but also to signals dependent on other macromolecular pathways of the cell, e.g., a defect in the secretory pathway leads to severe ...
Yu Zhao, Jung-Hoon Sohn, Jonathan R. Warner   +2 more
openaire   +3 more sources

Increased impairment of cerebral autoregulation in COVID-19 associated pulmonary failure requiring extracorporeal membrane oxygenation

Frontiers in Medicine
IntroductionCerebrovascular complications are feared but also commonly reported in patients with COVID-19 requiring extracorporeal membrane oxygenation (ECMO) support therapy.
Marcus Thudium, Jochen Kappler, Maximilian J. G. Oremek, Stefan Felix Ehrentraut, Evgeniya Kornilov, Milka Marinova, Christian Putensen, Martin Soehle, Jens-Christian Schewe, Jens-Christian Schewe   +9 more
doaj   +1 more source

Mathematical methods for modeling the microcirculation

AIMS Biophysics, 2017
The microcirculation plays a major role in maintaining homeostasis in the body. Alterations or dysfunctions of the microcirculation can lead to several types of serious diseases. It is not surprising, then, that the microcirculation has been an object of
Julia C. Arciero, Paola Causin, Francesca Malgaroli   +2 more
doaj   +1 more source

Regulation of Blood Flow in the Cerebral Posterior Circulation by Parasympathetic Nerve Fibers: Physiological Background and Possible Clinical Implications in Patients With Vertebrobasilar Stroke

Frontiers in Neurology, 2021
Posterior circulation involves the vertebrobasilar arteries, which supply oxygen and glucose to vital human brainstem structures and other areas. This complex circulatory- perfusion system is not homogenous throughout the day; rather, its hemodynamic ...
Arturo Tamayo, Arturo Tamayo, Timo Siepmann, Timo Siepmann   +3 more
doaj   +1 more source

Genetic noise control via protein oligomerization [PDF]

, 2008
Gene expression in a cell entails random reaction events occurring over disparate time scales. Thus, molecular noise that often results in phenotypic and population-dynamic consequences sets a fundamental limit to biochemical signaling.
A Arkin, A Barabasi, A Gilman, A Goldbeter, A Hernday, A Ujvari, B Alberts, B Chen, B Kim, B Lewin, B Müller-Hill, C Berger, C Herman, C Huang, C Tan, Cheol-Min Ghim, D Beckett, D Gillespie, D Hawley, D Hawley, D Rentzeperis, D Rozanov, D Thieffry, E Kussel, E Levine, Eivind Almaas, F Ramirez, F Sauer, G Ackers, H Kobayashi, I Ispolatov, J Kohler, J Little, J McDermott, J Newman, J Pedraza, J Raser, J Vilar, M Gibson, M Ptashne, M Shea, M Thattai, M Thattai, N Buchler, N Nelson, N Rosenfeld, P Guptasarma, P Warren, PL deHaseth, R Bundschuh, R Losick, R Sauer, S Macnamara, S Ramsey, S Semsey, T Alarcón, T Gardner, T Tian, T Tian, T Yi, WH Press   +60 more
core   +4 more sources