Results 71 to 80 of about 103,155 (374)
Gene autoregulation via intronic microRNAs and its functions [PDF]
, 2012 Background: MicroRNAs, post-transcriptional repressors of gene expression, play a pivotal role in gene regulatory networks. They are involved in core cellular processes and their dysregulation is associated to a broad range of human diseases.
Baroudi, Mariama El +4 more
core +2 more sources
Transcriptional Autoregulation by BRCA1 [PDF]
Cancer Research, 2010 Abstract The BRCA1 gene product plays numerous roles in regulating genome integrity. Its role in assembling supermolecular complexes in response to DNA damage has been extensively studied; however, much less is understood about its role as a transcriptional coregulator. Loss or mutation is associated with hereditary breast and ovarian
de Siervi, Adriana +9 more
openaire +3 more sources
Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
Med Research, EarlyView.The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
Minimum area of forests left to spontaneous development in protected areas
Journal of Forest Science, 2003 Search for ecological criteria for decisions on forests to be left to spontaneous development in specially protected areas is based on the knowledge of regularities of autochthonous or natural forests.
S. Vacek
doaj +1 more source
Photoplethysmography for Quantitative Assessment of Sympathetic Nerve Activity (SNA) During Cold Stress [PDF]
, 2019 The differences in the degree of sympathetic nerve activity (SNA) over cutaneous blood vessels, although known to be more prominent in the periphery than the core vasculature, has not been thoroughly investigated quantitatively.
Ainslie +43 more
core +2 more sources
Medicine Advances, EarlyView.Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang +6 more
wiley +1 more source
Critical Care Medicine, 2020 OBJECTIVES Monitoring cerebral autoregulation may help identify the lower limit of autoregulation in individual patients. Mean arterial blood pressure below lower limit of autoregulation appears to be a risk factor for postoperative acute kidney injury ...
Xiuyun Liu +12 more
semanticscholar +1 more source
Autoregulation of the tyrR gene [PDF]
Journal of Bacteriology, 1982 Strains of Escherichia coli K-12 in which the transcription of lacZ is initiated from the tyrR promoter have been constructed by use of the Mu d (Apr lac) phage of Casadaban and Cohen (Proc. Natl. Acad. Sci. U.S.A. 76:4530-4533, 1979). These strains have been used to examine the regulation of expression from the tyrR promoter, with the synthesis of ...
H, Camakaris, J, Pittard
openaire +2 more sources
Acute Stroke Multimodal Imaging: Present and Potential Applications toward Advancing Care. [PDF]
, 2017 In the past few decades, the field of acute ischemic stroke (AIS) has experienced significant advances in clinical practice. A core driver of this success has been the utilization of acute stroke imaging with an increasing focus on advanced methods ...
Liang, John W. +3 more
core +2 more sources
Relevance of dynamic cerebral autoregulation after acute ischemic stroke with prognosis: A protocol for systematic review and meta-analysis [PDF]
, 2022 Kai Wang +7 more
openalex +1 more source