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Assessing Risk of Rapid Progression in Autosomal Dominant Polycystic Kidney Disease and Special Considerations for Disease-Modifying Therapy.

American Journal of Kidney Diseases, 2021
Autosomal Dominant Polycystic Kidney Disease is the most common inherited cause of kidney failure accounting for 5-10% of cases. Predicting which patient would progress rapidly to kidney failure is critical to assess the risk-benefit ratio of any ...
F. Chebib, V. Torres
semanticscholar   +1 more source

Metformin Improves Relevant Disease Parameters in an Autosomal Dominant Polycystic Kidney Disease Mouse Model.

AJP - Renal Physiology, 2021
Autosomal dominant polycystic kidney disease (ADPKD), caused by mutations in the PKD1 or PKD2 genes encoding polycystins, presents with progressive development of kidney cysts and eventual end-stage kidney disease (ESKD) with limited treatment options ...
N. Pastor-Soler   +7 more
semanticscholar   +1 more source

Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease

NEJM Evidence, 2021
Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease The effect of increased water intake on kidney cyst growth in patients with polycystic kidney disease was compared for two groups randomly assigned to either prescribed or ad libitum
Gopi K Rangan   +24 more
semanticscholar   +1 more source

Activation of NRF2 ameliorates oxidative stress and cystogenesis in autosomal dominant polycystic kidney disease

Science Translational Medicine, 2020
Pharmacological induction of NRF2 restores redox homeostasis and slows cystogenesis in mouse models of polycystic kidney disease. Antioxidants dominate ADPKD Autosomal dominant polycystic kidney disease (ADPKD) is a relatively common genetic disorder ...
Yi Lu   +14 more
semanticscholar   +1 more source

Autosomal dominant polycystic kidney disease.

American Family Physician, 2014
A. Srivastava, Neel Patel
semanticscholar   +2 more sources

Autosomal dominant polycystic kidney disease

The Lancet, 1992
V. Torres, P. Harris, Y. Pirson
semanticscholar   +1 more source

Autosomal dominant polycystic kidney disease.

New England Journal of Medicine, 2010
P. Gabow
semanticscholar   +1 more source

Autosomal dominant polycystic kidney disease.

American Journal of Kidney Diseases, 1993
P. Gabow
semanticscholar   +1 more source

Onconephrology: The intersections between the kidney and cancer

Ca-A Cancer Journal for Clinicians, 2021
, Kenar D Jhaveri, Mark A Perazella
exaly  

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