Results 51 to 60 of about 30,053 (265)

Autosomal Dominant Polycystic Kidney Disease Patients Requiring Nephrectomy: Characteristics and Surgical Considerations

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Nephrectomies are major surgeries often required in ADPKD for symptom control, removal of septic/malignant foci, and to create space for renal transplantation. Whether ADPKD patients should proceed with nephrectomy/ies should be guided by patient characteristics, technical considerations and anticipated risks and benefits. Methods A
Joel Ern Zher Chan, Kate S. Olakkengil, Shantanu Bhattacharjya, Santosh Antony Olakkengil   +3 more
wiley   +1 more source

Robot‐assisted vs open kidney transplantation from deceased donors

BJU International, EarlyView.
Objectives To test the hypothesis that the type of surgical approach, robot‐assisted kidney transplantation (RAKT) vs open kidney transplantation (OKT), impacts intra‐operative and postoperative surgical outcomes of patients receiving kidney transplantation from deceased donors.
Luca Afferi, Angelo Territo, Alessio Pecoraro, Lorenzo Masieri, Milla Ortved, Julia Abildgaard Dagnæs‐Hansen, Begonya Etcheverry, Andrea Gallioli, Donato Cannoletta, Joris Vangeneugden, Jeremy Mercier, Thomas Prudhomme, Isacco Donnini, Antonino Vazzana, Malene Rohrsted, Francesc Vigués, Nicolas Doumerc, Karel Decaestecker, Joan Palou, Riccardo Campi, Sergio Serni, Andreas Roder, Alberto Breda   +22 more
wiley   +1 more source

Combined Liver and Kidney Transplant in a Patient with Budd-Chiari Syndrome Secondary to Autosomal Dominant Polycystic Kidney Disease Associated with Polycystic Liver Disease: Report of a Case with a 9-Year Follow-Up

Case Reports in Gastrointestinal Medicine, 2014
Polycystic liver disease (PLD) is a hereditary disease inherited by autosomal dominant trait that occurs as a frequent extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD).
Patricia Ramírez de la Piscina, Ileana Duca, Silvia Estrada, Rosario Calderón, Idoia Ganchegui, Amaia Campos, Katerina Spicakova, Leire Urtasun, Marta Salvador, Elvira Delgado, Raquel Bengoa, Francisco García-Campos   +11 more
doaj   +1 more source

Autosomal Dominant Polycystic Kidney Disease and Pericardial Effusion

Oman Medical Journal, 2018
The autosomal dominant polycystic kidney disease (ADPKD) accounts for one out of 400–1000 live births, being a hereditary disorder with cystic and noncystic manifestations as well as extrarenal involvement. The pericardial effusion (PE) in the context of
Guillermo Alberto Perez Fernandez, Montaser Y. Ismail   +1 more
doaj   +1 more source

Chronic brucellosis with hepatic brucelloma and AA amyloidosis in a patient with autosomal dominant polycystic kidney disease

Autopsy and Case Reports, 2020
We describe an autopsy case of a 45-year-old male diagnosed with autosomal dominant polycystic kidney disease who presented with complaints of altered sensorium.
Arpitha Kollabathula, Vikarn Vishwajeet, Kirti Gupta, Suvradeep Mitra, Vibhav Sharma, Pallab Ray, Ashish Bhalla   +6 more
doaj   +1 more source

Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C, Kruger, Samantha L, Shillingford, Jonathan M, Torres, Jacob, Weimbs, Thomas   +4 more
core   +1 more source

Sirolimus and kidney growth in autosomal dominant polycystic kidney disease [PDF]

, 2010
BACKGROUND: In autosomal dominant polycystic kidney disease (ADPKD), aberrant activation of the mammalian target of rapamycin (mTOR) pathway is associated with progressive kidney enlargement. The drug sirolimus suppresses mTOR signaling. METHODS: In this
Kistler, A D, Krauer, F, Kristanto, P, Poster, D, Raina, S, Rentsch, K M, Scheffel, H, Senn, O, Serra, A L, Spanaus, K S, Weishaupt, D, Wüthrich, R P, Young, J   +12 more
core   +1 more source

Multiple cerebral aneurysms in an adult with autosomal recessive polycystic kidney disease [PDF]

, 2021
[Extract] Autosomal recessive polycystic kidney disease(ARPKD) is a rare form offibrocystic kidneydisease that affects approximately 1 in 20,000 live births.
Clouston, John, Gately, Ryan, Hawley, Carmel, Lock, Gregory, Mallett, Andrew, Patel, Chirag   +5 more
core   +1 more source

Hypertension in Autosomal Dominant Polycystic Kidney Disease [PDF]

Advances in Chronic Kidney Disease, 2010
Hypertension is common and occurs in a majority of autosomal dominant polycystic kidney disease (ADPKD) patients before the loss of kidney function. Hypertension relates to progressive kidney enlargement and is a significant independent risk factor for progression to ESRD.
Konrad Stepniakowski, Frederic F. Rahbari-Oskoui, Arlene B. Chapman   +2 more
openaire   +3 more sources

Defining the polycystin pharmacophore through high‐throughput screening and computational biophysics

British Journal of Pharmacology, EarlyView.
An unbiased high throughput electrophysiology screen identifies potent PKD2L1 channel inhibitors with divergent chemical composition that bind to pore fenestration receptors and stabilise their inactivated state. Abstract Background and Purpose Polycystins (PKD2, PKD2L1) are voltage‐gated and Ca2+‐modulated members of the TRP family of ion channels ...
Eduardo Guadarrama, Carlos G. Vanoye, Paul G. DeCaen   +2 more
wiley   +1 more source