Results 41 to 50 of about 128,582 (263)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
AvocettaOn November 23rd, 2023, a Gray Catbird Dumetella carolinensis was found dead inside the Genoa Pra’ port terminal. This is the first record for Italy. The bird's condition suggests that death occurred approximately 20 days before it was found. On October
Alessandro Ghiggi
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Addressing cultural insensitivity in archival description
Journal of New Librarianship, 2020 Issues surrounding inappropriate language use in library cataloging and archival description have a history of discussion. This literature review examines biased language in library and archive use for collection description and explores collaborative ...
Autumn Wetli
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Seasonal climate summary for the southern hemisphere (autumn 2018): a weak La Niña fades, the austral autumn remains warmer and drier [PDF]
Journal of Southern Hemisphere Earth Systems Science, 2020 This is a summary of the austral autumn 2018 atmospheric circulation patterns and meteorological indices for the southern hemisphere, including an exploration of the season's rainfall and temperature for the Australian region.
Katie Rosemond, Bernard Chapman
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
EXPRESSIONIST ECHOES IN “3 AUTUMN” SONGS BY DAN VOICULESCU - STRUCTURE, STYLE, LANGUAGE
Studia Universitatis Babeş-Bolyai. Musica, 2012 The present study advances for analysis the lieder cycle 3 Autumn songs for soprano, oboe, two clarinets and violin from composer Dan Voiculescu’s youth.
Şerban MARCU
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