Results 131 to 140 of about 498,130 (293)

A 128-Channel 0.2-8.2 V Calibrated DAC IC Achieving 0.26-LSB DNL and 0.71-LSB DVO for Photonic Computing. [PDF]

Micromachines (Basel)
Li L, Lv D, Lv J, Li D, Du L, Du Y.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Correlated Noise Reduction in a CMOS ECG Amplifier: Opportunities and Limitations. [PDF]

Sensors (Basel)
Olivieri R, Tatangelo G, Khanehbeygi M, Barile G, Pantoli L, Stornelli V, Ferri G.   +6 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Ladies Auxiliary to the Long Beach Fire Department

, 1948
Ladies Auxiliary members in society dress (and many with hats) pose outside by pillars at the front of the Victor Hugo ...

core  

Tuning of AMPA receptor activation by inhibitory auxiliary subunits and epilepsy-associated disease mutations. [PDF]

Nat Commun
Newton TP, Yelshanskaya MV, Aktolun M, Gangwar SP, Yen LY, Alekseev AA, Sobolevsky IA, Kurnikova MG, Sobolevsky AI.   +8 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Ladies Auxiliary to the Long Beach Fire Department

, 1949
Members of Ladies Auxiliary with corsages pose in front of artificial Christmas ...

core  

Printing-Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling. [PDF]

Adv Sci (Weinh)
Moore SR, King N, Da Silva AC, Howarth C, Berwick J, Paterson TE, Minev IR.   +6 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source