Results 81 to 90 of about 1,238,433 (289)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Influence of film forming substrate on self-organized gradient structure of fluoroacrylate/polyurethane composite emulsion

Cailiao gongcheng, 2020
Fluoroacrylate/polyurethane composite emulsion (FPAPU) were synthesized by miniemulsion polymerization. The effect of four kinds of materials with different surface properties (aluminum plate, stainless steel plate, PTFE plate and glass plate) on the ...
XIN Hua, LIU Jian-fang, YANG Jiang-peng, ZHANG Hui, ZHAO Xing   +4 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

High-cycling-stability of Nanosized Sandwich Structure Silicon/Graphene Composite as Anode for Lithium-Ion Batteries

International Journal of Electrochemical Science, 2017
The nanosized sandwich structure silicon/graphene composite anode material was designed to enhance anode performance for lithium-ion batteries (LIBs) by a facile method of mechanical ball milling.
Rui Yang, Yiding Shen, Xiaowu Yang, Liewei Qiu, Xin Li   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Auxiliaries

, 2013
It is impossible to provide a definition of “auxiliary” that is consistent with all of its uses in the literature, but the term is most often used to refer to elements that express (or are involved in the expression of) clause-level distinctions such as tense, aspect, mood, modality, voice, agreement, polarity, and evidentiality.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Analytic Bethe Ansatz and Baxter equations for long-range psl(2|2) spin chain

, 2007
We study the largest particle-number-preserving sector of the dilatation operator in maximally supersymmetric gauge theory. After exploring one-loop Bethe Ansatze for the underlying spin chain with psl(2|2) symmetry for simple root systems related to ...
A.V. Belitsky, Balantekin, Bares, Bars, Baxter, Baxter, Bazhanov, Bazhanov, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Beisert, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Belitsky, Braun, Braun, Brink, Brink, Bukhvostov, Cherednik, Cherednik, Dorey, Eßler, Eßler, Eßler, Faddeev, Foerster, Frappat, Fulton, Gates, Grozman, Gunaydin, Gunaydin, Göhmann, Janik, Kac, Kac, Kazakov, Kirillov, Klümper, Krichever, Kulish, Kulish, Kulish, Kulish, Kuniba, Kuniba, Kuniba, Lipan, Lipatov, Lipatov, Lipatov, Mandelstam, Mandelstam, Minahan, Reshetikhin, Reshetikhin, Reshetikhin, Reshetikhin, Reshetikhin, Reshetikhin, Schoutens, Sklyanin, Sklyanin, Sklyanin, Staudacher, Tsuboi, Tsuboi, Tsuboi, Woynarowich, Yang, Zwiebel   +85 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source