Results 51 to 60 of about 43,626 (351)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Auxiliary Converter with Voltage Closed-loop Control

Kongzhi Yu Xinxi Jishu, 2012
According to the operation characteristics of auxiliary converter, based on voltage closed-loop and constant control strategy of the ratio between voltage and frequency square, it studied output voltage fluctuation of auxiliary converter and heavy load ...
TANG Zihui, JIANG Xuejun, WEI Gang
doaj  

A High Step-Up PWM Non-Isolated DC-DC Converter With Soft Switching Operation

IEEE Access, 2022
A high step-up PWM non-isolated dc–dc converter with soft switching is proposed in this paper. The converter has minimum auxiliary elements to achieve high power density and high voltage gain.
Shokouh Shabani, Majid Delshad, Ramtin Sadeghi, Hassan Haes Alhelou   +3 more
doaj   +1 more source

Auxiliary Power Supplies for High-Power Converter Submodules: State of the Art and Future Prospects [PDF]

, 2021
Stefanie Heinig, Keijo Jacobs, Kalle Ilves, Staffan Norrga, Hans‐Peter Nee   +4 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Capacitorless DC–DC regulator as a candidate topology for photovoltaic solar facilities [PDF]

, 2015
Postprint (published ...
Martínez García, Herminio
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Design of Auxiliary Converter for HXD1C Electric Locomotive

Kongzhi Yu Xinxi Jishu, 2010
This paper presents the main circuit, technical parameters and general structure of the auxiliary converter for HXD1C six-axle electric locomotive with 7 200 kW.
刘长清, 王佳佳, 蹇芳, 周文勇, 张宁   +4 more
doaj  

Research and implementation of double-tube flyback auxiliary power supply with high-voltage and wide-range input

Dianzi Jishu Yingyong, 2018
According to power supply requirements of power electronic converter with high-voltage and wide-range input，a double-tube flyback auxiliary switching power supply was designed. The operation principle of the double-tube flyback converter was analyzed. In
Feng Baogang, Zhang Lanhong, Lu Guangping   +2 more
doaj   +1 more source