Results 101 to 110 of about 3,788,461 (324)

Incremental localized boundary-domain integro-differential equations of elastic damage mechanics for inhomogeneous body [PDF]

, 2006
Copyright @ 2006 Tech Science PressA quasi-static mixed boundary value problem of elastic damage mechanics for a continuously inhomogeneous body is considered.
Mikhailov, SE
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Mean-field equation for a stochastic many-particle model of quorum-sensing microbial populations

, 2018
We prove a mean-field equation for the dynamics of quorum-sensing microbial populations. In the stochastic many-particle process, individuals of a population produce public good molecules to different degrees.
Frey, Erwin, Knebel, Johannes, Pickl, Peter   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Applications of dispersive analytical wave solutions of nonlinear seventh order Lax and Kaup-Kupershmidt dynamical wave equations

Results in Physics, 2019
In this article, new travelling wave solutions are constructed for two applications of the seventh order KdV equations, the seventh order Lax-equation and the seventh order Kaup-Kupershmidt equation.
Noufe H. Aljahdaly, Aly R. Seadawy, Wafaa A. Albarakati   +2 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

New oscillation results to fourth order delay differential equations with damping

Electronic Journal of Qualitative Theory of Differential Equations, 2016
This paper is concerned with the oscillation of the linear fourth order delay differential equation with damping \begin{equation*} \left(r_3(t)\left(r_2(t)\left(r_1(t)y'(t)\right)'\right)'\right)'+p(t)y'(t)+q(t)y(\tau(t))=0 \end{equation*} under the ...
Jozef Džurina, Blanka Baculíková, Irena Jadlovská   +2 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Auxiliary matrices on both sides of the equator [PDF]

Journal of Physics A: Mathematical and General, 2004
22 pages; 2nd version: one paragraph added in the conclusion and some typos ...
openaire   +2 more sources

Exact Solutions with Variable Coefficient Function Forms for Conformable Fractional Partial Differential Equations by an Auxiliary Equation Method

Advances in Mathematical Physics, 2018
In this paper, an auxiliary equation method is introduced for seeking exact solutions expressed in variable coefficient function forms for fractional partial differential equations, where the concerned fractional derivative is defined by the conformable ...
F. Meng, Qinghua Feng
semanticscholar   +1 more source